Granisetron 格拉司琼
CAS 109889-09-0 MFCD08063449
化学结构图
SMILES: [2H]C([2H])([2H])N1N=C(C(=O)N[C@@H]2C[C@@H]3CCC[C@H](C2)N3C)C2C=CC=CC1=2 |&1:10,12,16|
化学属性
| Mol. Formula | C18H21D3N4O |
|---|---|
| Mol. Weight | 315.433 |
别名和识别编码
| Chemical Name | Granisetron |
|---|---|
| Chemical Name Translation | 格拉司琼 |
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相关文献及参考
- [2]. Maleki-Dizaji N, Eteraf-Oskouei T, Fakhrjou A, The effects of 5HT3 receptor antagonist granisetron on inflammatory parameters and angiogenesis in the air-pouch model of inflammation. Int Immunopharmacol. 2010 Sep;10(9):1010-6.
- [3]. Boccia RV, Gordan LN, Clark G, Efficacy and tolerability of transdermal granisetron for the control of chemotherapy-induced nausea and vomiting associated with moderately and highly emetogenic multi-day chemotherapy: a randomized, double-blind, phase III study. Support Care Cancer. 2011 Oct;19(10):1609-17.
- [1]. Sanger GJ, Nelson DR. Selective and functional 5-hydroxytryptamine3 receptor antagonism by BRL 43694 (granisetron). Eur J Pharmacol. 1989 Jan 10;159(2):113-24.
- [1]. Sanger GJ, Nelson DR. Selective and functional 5-hydroxytryptamine3 receptor antagonism by BRL 43694 (granisetron). Eur J Pharmacol. 1989 Jan 10;159(2):113-24.
- [2]. Maleki-Dizaji N, Eteraf-Oskouei T, Fakhrjou A, The effects of 5HT3 receptor a
