CAS 111-20-6 MFCD00004440-Sebacic Acid 癸二酸 TAO{mole}

Sebacic Acid 癸二酸

CAS 111-20-6 MFCD00004440

化学结构图

SMILES: O=C(O)CCCCCCCCC(=O)O

化学属性

Mol. Formula	C10H18O4
Mol. Weight	202.25
Boiling Point	374.3 °C at 760 mmHg
Melting Point	131-134.5 °C
Density	1.271
Flash Point	220°(428°F)
TSCA	Yes
Vapor Pressure	1 mmHg ( 183 °C)
Solubility	微溶于水，溶于酒精和乙醚。
Stability	对湿度敏感
Appearance	白色片状结晶。微溶于水，溶于酒精和乙醚。
Refractive index	1.422

别名和识别编码

Chemical Name	Sebacic Acid
Synonym	Decanedioic acid {LY} Decanedioic acid {} {LY} Decanedioic acid {} {} {LY} Decanedioic acid {} {} {} {LY} Decanedioic acid {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Decanedioic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Beilstein Registry Number	1210591
PubChem Substance ID	87575652
CAS Number	111-20-6
EC Number	203-845-5
MDL Number	MFCD00004440
Reaxys-RN	1210591
Merck Number	8415
Chemical Name Translation	癸二酸
Wiswesser Line Notation	QV8VQ
LabNetwork Molecule ID	LN00197438
Canonical SMILES	O=C(O)CCCCCCCCC(O)=O

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

气相色谱减尾剂，分离分析脂肪酸，可用于沉淀及定量测定钍，并使钍与铈及其他稀土元索分离。增塑剂、合成树脂和合成纤维。

安全信息

WGK Germany1

RTECSVS0875000

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Signal word Warning

GHS Symbol

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Precautionary statements

P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P302+P352+P332+P313+P362+P364
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338
P332+P313
P305+P351+P338+P337+P313
P302+P350
P337+P313

Hazard statements

H315 Causes skin irritation 会刺激皮肤

Hazard Codes Xi

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {}

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6 gm/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   BIJOAK Biochemical Journal.  (Biochemical Soc. Book Depot, POB 32, Commerce
   Way, Colchester, Essex CO2 8HP, UK)  V.1-    1906- Volume(issue)/page/year:
   34,1196,1940

TYPE OF TEST            : LD50 - Lethal dose, 50 percen

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 14375 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Behavioral - food intake (animal)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 57(2),17,1992

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >4500 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 57(2),17,1992

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1175 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-

其他信息

常规方法:用编织袋或麻袋内衬塑料袋包装，每袋净重25、40、45或50kg。贮存于阴凉通风处，防火防潮。勿与液酸和碱混放。按易燃品规定贮运。
下游产品:清洗剂 --> 14-甲基十五烷酸 --> 褐煤酸 --> 1-芘癸酸 --> 1,10-癸二醇 --> 癸二酸二丁酯 --> 癸二酸二异辛酯 --> 尼龙-1010 --> 癸二酸二辛酯 --> 仲辛醇 --> 癸二酸二乙酯 --> 癸二
灭火剂:干粉、泡沫、砂土, 水
能溶于醇类、酯类和酮类，
毒性分级:低毒
主要制备方法:(1)以蓖麻油为原料，将其中的蓖麻醇酸分离出来，与苛性钠在加压及280～300℃ 下进行碱熔，加热反应10h，可制得皮脂酸的钠盐，同时副产2-辛醇。将钠盐溶于水，加入硫酸中和，脱色后，将溶液冷却，析出皮脂酸，用冷水洗，最后重结晶。 CH3(CH2)5CH(OH)CH2CH=CH(CH2)7COOH+ 2NaOH→CH3(C
上游原料:氢氧化钠 --> 硫酸 --> 四氯化碳 --> 蓖麻油 --> 环戊酮 --> 挥发性漆稀释剂 --> 环戊烯 --> 单酯 --> 200#溶剂油 --> 癸烷 --> 癸二酸双钠盐 --> 润滑脂 --> 癸二酸单钠盐 --> 蓖麻油酸钠
Alfa Aesar:癸二酸,98+% Sebacic acid, 98+%(111-20-6)
方法一:以天然的蓖麻油或已二酸单酯为原料制得。用乙烯、四氯化碳经聚合反应也可得到癸二酸，但目前世界上工业生产的癸二酸几乎全部都是用蓖麻油作原料的。1.蓖麻油裂解法蓖麻油在碱作用下加热水解生成蓖麻油酸钠皂，然后加硫酸酸解生成蓖麻油酸；在稀释剂甲酚的存在下，加碱加热到260-280℃进行裂解，生成癸二酸双钠盐及仲辛醇和氢气，裂解物经水稀释后，加热加酸中和，把双钠盐变成单钠盐；再用活性炭脱色后的中和液煮沸加酸，使癸二酸单钠盐变成癸二酸结晶析出，再经分离、干燥即得成品。原料消耗定额：蓖麻油（工业品）2100kg/t、硫酸（98%）1600kg/t、烧碱（95%）1200kg/t、甲酚（工业品）100kg/t。2.石油正癸烷发酵法利用200＃溶剂油或166－182℃馏分中分离制得的正癸烷，以19-2解脂假丝酵母发酵制得癸二酸。3.新环戊酮法以钯盐-铜或铁为催化剂，在乙醇、丙醇或其他醇的溶剂中，在40－60℃低温和常压的缓和条件下，将环戊烯用空气氧化生成环戊酮，然后用铁催化剂氧化和二聚而成。
TCI Shanghai:癸二酸 Sebacic Acid,>;98.0%(GC)(T)(111-20-6)
用途三:主要用作癸二酸酯类增塑剂和尼龙塑模树脂的原料，还可用作耐高温润
类别:易燃液体
皮脂酸价格(试
MOL 文件:111-20-6.mol
用途三:主要用作癸二酸酯类增塑剂和尼龙塑模树脂的原料，还可用作耐高温润滑油的原料。其主要酯类
图谱信息:皮脂酸(111-20-6)
急性毒性:口服- 大鼠 LD50: 14375 毫克/ 公斤; 口服- 小鼠 LD50: 6000 毫克/ 公斤
Acros Organics:Sebacic acid, pract., 90%(111-20-6)
储运特性:库房通风低温干燥
用途二:用作分析试剂等
防护措施:癸二酸基本无毒，但生产中所用甲酚有毒，要防止中毒（参见甲酚）。生产设备应密闭。操作人员应戴口罩及手套。
上游原料:氢氧化钠 --> 硫酸 --> 四氯化碳 -
皮脂酸价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 30163860 癸二酸;辛二甲酸;皮脂酸 250g 35元 2011/08/23 40050960 癸二酸;辛二甲酸;皮脂酸 25g 12.3元 2011/08/23 40050961 癸二酸;辛二甲酸;皮脂酸 25g 12.3元
用途一:用作耐寒增塑剂、树脂及尼龙等的原料