Atazanavir 阿扎那韦
CAS 198904-31-3 MFCD98904313
化学结构图
SMILES: CC(C)(C)[C@H](NC(=O)OC)C(=O)N[C@@H](CC1C=CC=CC=1)[C@@H](O)CN(CC1C=CC(=CC=1)C1C=CC=CN=1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C
化学属性
| Mol. Weight | 705 |
|---|---|
| Mol. Formula | C38H52N6O7 |
别名和识别编码
| CAS Number | 198904-31-3 |
|---|---|
| Chemical Name | Atazanavir |
| Synonym | 3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-dimethyl Ester (3S,8S, 9S, 12S)-2,5,6,13-Pentaazatetradecanedioic Acid BMS-232632 CGP-73547 |
| Chemical Name Translation | 阿扎那韦 |
| LabNetwork Molecule ID | LN01272250 |
| MDL Number |
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分类
- Chiral Reagents
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral.
相关文献及参考
- [2]. Wood R. Atazanavir: its role in HIV treatment. Expert Rev Anti Infect Ther. 2008 Dec;6(6):785-96.
- [3]. Qi Sun, et al. Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease. Signal Transduct Target Ther. 2021 May 29;6(1):212.
- Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004),
- Nolan, D., et al.: Drugs, 63(23), 2555 (2003),
- Palella, F.J. Jr., et al.: N. Engl. J. Med., 338(13), 853 (1998),
- [1]. Havlir DV, et al. Atazanavir: new option for treatment of HIV infection. Clin Infect Dis. 2004 Jun 1;38(11):1599-604.
- [1]. Havlir DV, et al. Atazanavir: new option for treatment of HIV infection. Clin Infect Dis. 2004 Jun 1;38(11):1599-604.
- [2]. Wood R. Atazanavir: its role in HIV treatment. Expert Rev Anti Infect Ther. 2008 Dec;6(6):785-96.
- [3]. Qi Sun, et al. Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical tri
