CAS 23109-05-9 MFCD00215842-α-Amanitin Α-毒伞肽 TAO{mole}

α-Amanitin Α-毒伞肽

CAS 23109-05-9 MFCD00215842

化学结构图

SMILES: CCC(C)[C@@H]1NC(=O)CNC(=O)[C@H]2CC3C4C=CC(O)=CC=4NC=3S(=O)C[C@@H](NC(=O)CNC1=O)C(=O)N[C@H](CC(N)=O)C(=O)N1CC(C(O)C1)C(=O)N[C@@H]([C@@H](C)[C@@H](O)CO)C(=O)N2

化学属性

Mol. Formula	C39
Mol. Weight	919
Melting Point	254-255 °C(lit.)

别名和识别编码

Chemical Name	alpha-Amanitine
PubChem Substance ID	24890639
EC Number	245-432-2
Beilstein Registry Number	1071138
MDL Number	MFCD00215842
Synonym	alpha-Amatoxin α-Amanitin alpha-Amanitin
Chemical Name Translation	Α-毒伞肽
CAS Number	23109-05-9
Wiswesser Line Notation	T C6 B5 R5-18--18-/MP& A K L 2BJ P& IM KS NVM QVN WVMC&VM F&VM I&VM L&VM O&VM&&TTTJ FQ KO P1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

GHS Symbol

WGK Germany3

Hazard statements

H330 Fatal if inhaled 吸入致命
H310 Fatal in contact with skin 皮肤接触致命
H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
H300 Fatal if swallowed 吞食致命

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

RTECSBD6195000

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P301+P310
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P302+P350
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。

Signal word Danger

Hazard Codes T+

Risk Statements

R33 Danger of cumulative effects 有累积作用的危险
R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒

Safety Statements

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEJMAG New England Journal of Medicine.  (Massachusetts Medical Soc., 10
   Shattuck St., Boston, MA 02115)  V.198-    1928-  Volume(issue)/page/year:
   269,223,1963

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 22,2142,1972

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 100 nmol/L
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 25,1265,1987

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Int

TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1 mg/kg
REFERENCE :
   BBACAQ Biochimica et Biophysica Acta.  (Elsevier Science Pub. B.V., POB 211,
   1000 AE Amsterdam, Netherlands)  V.1-    1947- Volume(issue)/page/year:
   782,262,1984

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Insect - Drosophila melanogaster Cells - not
                          otherwise specified
DOSE/DURATION           : 20 mg/L
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology.  (Publications & Information
   Directorate, CSIR, Hillside Rd., New Delhi 110 012, India)  V.1-    1963-
   Volume(issue)/page/year:

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 125 mg/L
REFERENCE :
   AMICCW Archives of Microbiology.  (Springer-Verlag New York, Inc., Service
   Center, 44 Hartz Way, Secacus, NJ 07094)  V.95-    1974-
   Volume(issue)/page/year: 118,317,1978

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Insect - not otherwise specified Cells - not
                          otherwise specified
DOSE/DURATION           : 10 ug
REFERENCE :
   BBACAQ Biochimica et Biophysica Acta.  (Elsevier Science Pub. B.V., POB 211,
   1000 AE Amsterdam, Netherlands)  V.1-    1947- Volume(issue)/page/year:
   697,213,1982