(αS)-α-[(2,6-Dichlorobenzoyl)amino]-2′,6′-dimethoxy[1,1′-biphenyl]-4-propanoic acid (αs)-α-[(2,6-二氯苯甲酰基)氨基]-2',6'-二甲氧基[1,1'-Biphenyl]-4-丙酸
CAS 232271-19-1 MFCD32271191
化学结构图
SMILES:
化学属性
| Mol. Formula | C24H21Cl2NO5 |
|---|
别名和识别编码
| Chemical Name | (αS)-α-[(2,6-Dichlorobenzoyl)amino]-2′,6′-dimethoxy[1,1′-biphenyl]-4-propanoic acid |
|---|---|
| Chemical Name Translation | (αs)-α-[(2,6-二氯苯甲酰基)氨基]-2',6'-二甲氧基[1,1'-Biphenyl]-4-丙酸 |
| Chemicalbook ID | CB12565722 |
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相关文献及参考
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- [3]. Julio Cortijo, et al. A small molecule, orally active, α4β1/α4β7 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic asthma in Brown Norway rats. Br J Pharmacol. 2006 Mar; 147(6): 661–670.
- [4]. M Tsuda-Tsukimoto, et al. Pharmacokinetics and metabolism of TR-14035, a novel antagonist of a4ss1/a4ss7 integrin mediated cell adhesion, in rat and dog. Xenobiotica
- [1]. Sircar I, et al. Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alph
- [1]. Sircar I, et al. Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist. Bioorg Med Chem. 2002 Jun;10(6):2051-66.
