N-(Deoxyguanosin-8-yl)-2-amino-1-(methyl-d3)-6-phenylimidazo[4,5-?]pyridine
CAS 303173-39-9 MFCD04039493
化学结构图
SMILES: NC1NC(=O)C2N=C(NC3=NC4=NC=C(C=C4N3C([*])([*])[*])C3C=CC=CC=3)N([C@@H]3C[C@@H](O)[C@H](CO)O3)C=2N=1 |&1:29,31,33,$;;;;;;;;;;;;;;;;;;;2H;2H;2H;;;;;;;;;;;;;;;;;$|
化学属性
| Mol. Weight | 492.51 |
|---|---|
| Mol. Formula | C23H20D3N9O4 |
别名和识别编码
| CAS Number | 303173-39-9 |
|---|---|
| Chemical Name | N-(Deoxyguanosin-8-yl)-2-amino-1-(methyl-d3)-6-phenylimidazo[4,5-?]pyridine |
| Synonym | 2'-Deoxy-8-[[1-(methyl-d3)-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl]amino]guanosine dG-C8-PhIP-d3 |
| Chemical Name Translation |
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分类
- Isotope Labelled Compounds
- Mutagenesis Research Chemicals
- Nucleotides
- Bases & Related Reagents
产品应用
- The deuterated DNA adduct formed from N-Hydroxy-PHIP. Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (D
相关文献及参考
- Frandsen, H., et al.: Carcinogenesis, 13, 4, 629 (1992),
- Lin, D., et al.: Chem. Res. Toxicol., 5, 691 (1993),
