Adiphenine HCl 阿地芬宁盐酸盐
CAS 50-42-0 MFCD00050508
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            分类
- {SNA} Additional Drugs, Additional Standards, Analytical Standards, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, Neat Compounds, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
 - {SNA} A, AA to AL, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites,
 - {SA} A, AA to AL, Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, Neat Compounds
 
安全信息
 GHS Symbol
 
        
            
            
 - P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
 - P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
 - P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
 - P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
 - P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
 - P301+P312
 - P302+P352
 - P302+P352+P312+P362+P364
 - P304+P312
 - P304+P340
 - P304+P340+P312
 - P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
 - P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
 - P330 Rinse mouth. 漱口
 - P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
 - P501 Dispose of contents/container to..… 处理内容物/容器.....
 
- H302 Harmful if swallowed 吞食有害
 - H302+H312+H332
 - H312 Harmful in contact with skin 皮肤接触有害
 - H332 Harmful if inhaled 吸入有害
 
- S36 Wear suitable protective clothing 穿戴适当的防护服;
 
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
 
TYPE OF TEST : LDL
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BDCBAD Berichte der Deutschen Chemischen Gesellschaft. Abteilung B: Abhandlungen. (Heidelberg, Fed. Rep. Ger.) V.62-77, 1929-45. For publisher information, see CHBEAM. Volume(issue)/page/year: 72,1551,1939
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes Cardiac - other changes REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 59,365,1937
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949
{hazarTYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 15 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes REFERENCE : JPETAB
其他信息
- 解痉素 盐酸盐
 - Adiphenine HCl 是一种烟碱受体抑制剂,IC50为15 μM,用作解痉药。
 
