CAS 544-31-0 MFCD00020562-Palmitoylethanolamide 十六酰胺乙醇 TAO{mole}

Palmitoylethanolamide 十六酰胺乙醇

CAS 544-31-0 MFCD00020562

化学结构图

SMILES: CCCCCCCCCCCCCCCC(=O)NCCO

化学属性

Mol. Formula	C18H37NO2
Mol. Weight	299.49
Solubility	Soluble in DMSO (20 mM), ethanol (25 mM), chloroform, THF ( at 30 °C), and DMF (~10 mg/ml).
Stability	对热敏感
Melting Point	97-98 °C
Boiling Point	461.5°C at 760 mmHg

别名和识别编码

Chemical Name	Palmitoylethanolamide
MDL Number	MFCD00020562
CAS Number	544-31-0
Synonym	Palmitoylethanolamide {LY} Palmitoylethanolamide {} {LY} Palmitoylethanolamide {} {} {LY} Palmitoylethanolamide {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Palmitoylethanolamide {} {} {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID	4671
EC Number	208-867-9
Chemical Name Translation	十六酰胺乙醇
LabNetwork Molecule ID	LN00330728
Merck Number	6995
InChI	InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
Canonical SMILES	CCCCCCCCCCCCCCCC(NCCO)=O

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产品应用

An endogenous cannabinoid agonist, FAAH inhibitor, and PPARα agonist

安全信息

WGK Germany2

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Storage condition -20°C {LY} -20°C 0-10°C {} {LY} -20°C {} {} {LY} -20°C {} {} {} {LY} -20°C {} {} {} {} {LY} -20°C {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

RTECSML8950000

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H318 Causes serious eye damage 严重伤害眼睛
H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P302+P352
P305+P351+P338
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P332+P313
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
P501 Dispose of contents/container to..… 处理内容物/容器.....

其他信息

Palmitoylethanolamide is an endogenous cannabinoid. It is a weak ligand of the cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptors. It has been found to inhibit FAAH (fatty acid amide hydrolase). Palmitoylethanolamide exhibits anti-nociceptive, anti-inflammatory, anti-convulsant and immunosuppresant activity. Palmitoylethanolamide acts by binding to an unidentified cannabinoid receptor that is similar to CB2. It also acts as a selective activator of the GPR55 receptor. In addition, this compound directly activates PPARα, producing an anti-inflammatory response.