Glycine 甘氨酸

CAS 56-40-6 MFCD00008131

化学结构图

56-40-6
SMILES:

化学属性

Mol. FormulaC2H5NO2
Mol. Weight75.07
Melting Point240°C
Density1.595
TSCAYes
Boiling Point>233
Solubility易溶于水,在水中的溶解度:25℃时为25g/100ml;50℃时为39.1g/100ml;75℃时为54.4g/100ml;100℃时为67.2g/100ml。极难溶于乙醇,在100g无水乙醇中约溶解0.06g。几乎不溶于丙酮和乙醚。
Appearance powder
Refractive index1.55

别名和识别编码

Chemical NameGlycine
Synonym AKOS 237-137 AKOS BBS-00003777 AMINOETHANOIC ACID Aciport Additive Screening Solution 47/Fluka kit no 78374 Additive Screening Solution 47/Fluka kit no 78374 Glycine solution Aminoacetic acid Aminoacetic acid; Glycocoll CESIUM NITRATE Cesium nitrate (99.9% Cs) Cesiumnitratewhitextl FEMA 3287 GLYCINE GLYCOCOL GLYCOCOLL Glycine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Beilstein Registry Number635782
CAS Number56-40-6
EC Number200-272-2
MDL NumberMFCD00008131
PubChem Substance ID87570306
Reaxys-RN635782
Merck Number4491
Chemical Name Translation甘氨酸
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
Wiswesser Line NotationZ1VQ
LabNetwork Molecule IDLN00195395
Canonical SMILESNCC(O)=O
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分类

  • {SNA} Acid, All Alphabetically Sorted, Amino Acids, Analytical Standards, Analytical/Chromatography, Certified Reference Materials (CRMs), Chromatography, E numbers (Food Additives), E600–E699 (flavor enhancers), E640, Flavors and Fragrances, Fluka CRM for chromatography (neats), Food & Beverage Standards, G-L, Organic Acids, Organic CRMs Alphabetical, Organic CRMs TraceCERT, Substance Classification
  • {SNA} Alphabetical, Amino Acids, BioUltra, BioUltra Buffers, Bioactive Small Molecules, Biochemicals and Reagents, Biological Buffers,

产品应用

  • 络合滴定指示剂,色层分析用试剂;缓冲剂;比色法测定氨基酸时作标准用。检验铜、金和银。制备组织培养基。在有机合成和生物化学中用作生化试剂和溶剂。
  • 脊髓抑制性神经递质,NMDA受体的变构调节
  • 分子生物学级用做缓冲液组分,在耦联磷酸激酶反应中用于末端标记限制性酶切片段;Tris -甘氨酸缓冲液组分,用于SDS -聚丙烯酰胺凝胶电泳中的体外翻译产物应用中。

相关文献及参考

  • Laemmli, U.K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 , 680-685, (1970) 摘要
  • Logue, S.E., et al., Expression, purification and use of recombinant annexin V for the detection of apoptotic cells. Nat. Protoc. 4 , 1383-95, (2009) 摘要
  • Merck 14 ,4491
  • Merck:14,4491
  • Merck:14,4491 Beilstein: 4,IV,2349
  • Rosner, M., et al., Efficient SiRNA-mediated Prolonged Gene Silencing In Human Amniotic Fluid Stem Cells. Nat. Protoc. 5 , 1081-95, (2010) 摘要
  • Røtterud, R., et al., The Star Chart To Ta Bladder Cancer: An Unsophisticated Analysis Of Two-dimensional Gel Electrophoresis Proteome Maps. Scand. J. Urol. Nephrol. 44 , 76-83, (2010) 摘要
  • Smith, K., et al., Rapid Generation Of Fully Human Monoclonal Antibodies Specific To A Vaccinating Antigen. Nat. Protoc. 4 , 372-84, (2009) 摘要
  • Yu, D., et al., Fractionation Of Different PEGylated Forms Of A Protein By Chromatography Using Env

安全信息

RTECSMB7600000
WGK Germany1
Signal word Warning
GHS Symbol
Safety Statements
  • S17 Keep away from combustible material 远离可燃物料;
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R8 Contact with combustible material may cause fire 遇到易燃物会导致起火
  • R33 Danger of cumulative effects 有累积作用的危险
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Personal Protective Equipment Eyeshields, Gloves Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 2-8°C 密封保存
Packing GroupIII
Hazard Codes O,Xi
Hazard Class5.1
UN Number UN 1451 5.1/PG 3
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5060 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 5,1502,1977

TYPE OF TEST            : LD50 - Lethal dose

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 5,1502,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4920 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 5,1502,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 5

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 280,279,1992

其他信息

  • 类别:氧化剂
  • 外观性质:白色结晶粉末, 易潮解, 有盐硝味。
  • 毒性分级:中毒
  • 急性毒性:口服- 大鼠 LD50: 2390 毫克/ 公斤; 口服- 小鼠 LD50: 2300 毫克/ 公斤
  • Sigma Aldrich:7789-18-6(sigmaaldrich)
  • Alfa Aesar:硝酸铯,99.999%(metalsbasis) Cesium nitrate, 99.999% (metals basis)(7789-18-6)
  • Acros Organics:Cesium nitrate, for analysis, 99.99%(7789-18-6)
  • 用途一:用作制取各种铯盐的基础原料,在催化剂、特种玻璃、陶瓷等方面有广泛用途
  • F:3
  • 敏感性:Hygroscopic
  • 爆炸物危险特性:与有机物、还原剂、硫、磷等易燃物混合可爆
  • 储运特性:库房通风; 轻装轻卸; 与有机物、还原剂、木炭、硫磷易燃物分开存放
  • MSDS 信息:硝酸铯(7789-18-6).msds
  • MOL 文件:7789-18-6.mol
  • 可燃性危险特性:遇有机物、还原剂、木炭、硫、磷等易燃物可燃; 燃烧产生有毒氮氧化物烟雾
  • 用途二:分析试剂、铯盐制造、氧化剂、钠的微量分析、环境控制分析中放射性物质的检测,石油化工业催化剂加剂,光纤中调节光折射率等. 本产品在分析试剂和某催化剂领域已应用多年.用于。
  • Glycine is widely used as a buffer for a variety of immunological applications. It is frequently used in the preparation of TG Buffers (Tris-Glycine) where the buffer is used as a running and/or transfer buffer for polyacrylamide gel electrophoresis and western blotting. Glycine (100 mM, pH 2.0-2.5) is also used as an eluent in column chromatography. Glycine has been reported for use in the enzymatic determination of lactate using lactic dehydrogenase.
  • 灭火剂:雾状水
  • 水中溶解度(g/100ml):不同温度(℃)时每100毫升水中的溶解克数: 9.33g/0℃;14.9g/10℃;23g/20℃;33.9g/30℃;47.2g/40℃ 83.8g/60℃;134g/80℃;163g/90℃;197g/100℃
  • 味甜。溶于水,微溶于吡啶,不溶于乙醚。25℃,100ml水中溶解度为25.0g,50℃为39.1g,75℃为54.4g,100℃为67.2g。热至233℃开始分解,290℃全部结块。最小致死量(猫,静脉)3000mg/kg。
  • 硝酸铯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80031312 硝酸铯(易制爆) 5g 60元 2010/06/21 192072500 硝酸铯 Cesium nitrate 99.99%, for analysis 250 GR 6654元 2010/06/21 195901000 硝酸铯 Cesium standard solution , for AAS, 1 mg/ml Cs in 2% HNO3 100 ML 569元
  • color:<;5 (200 mg/mL)(APHA)

系列性分类


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