1H-Benzo(de)(1,6)naphthyridine, 8,9-dimethoxy-
CAS 85547-22-4 MFCD01662128
化学结构图
SMILES: COC1=CC2=CC=NC3C=CNC(C2=3)=C1OC
化学属性
| Mol. Formula | C13H12N2O2 |
|---|---|
| Mol. Weight | 228.27 |
别名和识别编码
| Chemical Name | 1H-Benzo(de)(1,6)naphthyridine, 8,9-dimethoxy- |
|---|---|
| Synonym | Aaptamine 8,9-Dimethoxy-1H-benzo(de)(1,6)naphthyridine |
| Beilstein Registry Number | 3550089 |
| CAS Number | 85547-22-4 |
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相关文献及参考
- [2]. Aoki S, et al. Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner. Biochem Biophys Res Commun. 2006 Mar 31;342(1):101-6.
- [1]. Ohizumi Y, et al. Alpha-adrenoceptor blocking action of aaptamine, a novel marine natural product, in vascular smooth muscle. J Pharm Pharmacol. 1984 Nov;36(11):785-6.
- [1]. Ohizumi Y, et al. Alpha-adrenoceptor blocking action of aaptamine, a novel marine natural product, in vascular smooth muscle. J Pharm Pharmacol. 1984 Nov;36(11):785-6.
- [2]. Aoki S, et al. Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner. Biochem Biophys Res Commun. 2006 Mar 31;342(1):101-6.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal.
For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 24(7),15,1990