(R,E)-2-(4-(2-(5-(1-(3,5-Dichloropyridin-4-Yl)Ethoxy)-1H-Indazol-3-Yl)Vinyl)-1H-Pyrazol-1-Yl)Ethan-1-Ol (R,E)-2-(4-(2-(5-(1-(3,5-二氯吡啶-4-基)乙氧基)-1H-吲唑-3-基)乙烯基)-1H-吡唑-1-基)乙醇
CAS 1254473-64-7 MFCD354473647
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- LY2874455 is a novel and potent FGF/FGFR Inhibitor. It exhibits a potent activity against FGF/FGFR-mediated signaling in several cancer cell lines and shows an excellent broad spectrum of antitumor activity in several tumor xenograft models representing the major FGF/FGFR relevant tumor histologies including lung, gastric, and bladder cancers and multiple myeloma, and with a well-defined pharmacokinetic/pharmacodynamic relationship.