Rotigotine Hydrochloride 盐酸罗替戈汀
CAS 125572-93-2 MFCD25572932
化学结构图
SMILES: CCCN(CCC1=CC=CS1)[C@@H]1CC2=CC=CC(O)=C2CC1
化学属性
| Mol. Weight | 351.91 |
|---|---|
| Mol. Formula | C19H26ClNOS |
别名和识别编码
| CAS Number | 125572-93-2 |
|---|---|
| Chemical Name | Rotigotine Hydrochloride |
| Synonym | (6S)- |
| LabNetwork Molecule ID | LN01374802 |
| Chemical Name Translation | 盐酸罗替戈汀 |
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分类
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds,
产品应用
- It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson?s disease.
相关文献及参考
- [2]. Scheller D, et al. The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease. Naunyn Schmiedebergs Arch Pharmacol. 2009 Jan;379(1):73-86.
- [3]. Fenu S, et al. In vivo dopamine agonist properties of rotigotine: Role of D1 and D2 receptors. Eur J Pharmacol. 2016 Oct 5;788:183-91.
- [4]. Radad K, et al. Neuroprotective effect of rotigotine against complex I inhibitors, MPP? and rotenone, in primary mesencephalic cell culture. Folia Neuropathol. 2014;52(2):179-86.
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- [1]. Wood M, et al. Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors. Br J Pharmacol. 2015 Feb;172(4):1124-35.
- [1]. Wood M, et al. Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors. Br J Pharmacol. 2015 Feb;172(4):1124-35.
- [2]. Scheller D, et al. The in vitro receptor profile of rotigotine: a new agent for the treatment of
