Rupatadine Fumarate 富马酸卢帕他定
CAS 182349-12-8 MFCD82349128
化学结构图
SMILES: CC1C=NC=C(CN2CCC(CC2)=C2C3N=CC=CC=3CCC3=CC(Cl)=CC=C32)C=1.OC(=O)/C=C/C(O)=O
化学属性
| Mol. Weight | 532.03 |
|---|---|
| Mol. Formula | C30H30ClN3O4 |
别名和识别编码
| CAS Number | 182349-12-8 |
|---|---|
| Chemical Name | Rupatadine Fumarate |
| Synonym | 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (2E)-2-Butenedioate Rupafin |
| Chemical Name Translation | 富马酸卢帕他定 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- Rupatadine is a dual antagonist of histamine H1 and platelet-activating factor receptors. Rupatadine is used as an antihistaminic.
相关文献及参考
- [2]. Queralt M, et al. In vitro inhibitory effect of rupatadine on histamine and TNF-alpha release from dispersed canine skin mast cells and the human mast cell line HMC-1. Inflamm Res. 2000 Jul;49(7):355-60.
- [3]. Lv XX, et al. Rupatadine protects against pulmonary fibrosis by attenuating PAF-mediated senescence in rodents. PLoS One. 2013 Jul 15;8(7):e68631.
- Guadano, E.M., et al.: Allergy, 59, 766 (2004),
- Merlos, M., et al.: J. Pharmacol. Exp. Ther., 280, 114 (1997),
- [1]. Merlos M, et al. Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF). J Pharmacol Exp Ther. 1997 Jan;280(1):114-21.
- [1]. Merlos M, et al. Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF). J Pharmacol Exp Ther. 1997 Jan;280(1):114-21.
- [2]. Queralt M, et al. In vitro inhibitory effect of rupatadine on histamine and TNF-alpha release from dispersed canine
