2-Piperidinoethyl 4-Amino-5-Chloro-2-Methoxybenzoate 2-哌啶乙基-4-氨基-5-氯-2-甲氧基苯甲酸酯
CAS 186826-17-5 MFCD86826175
化学结构图
SMILES: COC1C=C(N)C(Cl)=CC=1C(=O)OCCN1CCCCC1
化学属性
| Mol. Weight | 349.25 |
|---|---|
| Mol. Formula | C15H22Cl2N2O3 |
别名和识别编码
| CAS Number | 186826-17-5 |
|---|---|
| Chemical Name | 2-Piperidinoethyl 4-Amino-5-Chloro-2-Methoxybenzoate |
| Synonym | 4-Amino-5-chloro-2-methoxybenzoic Acid 2-(1-Piperidinyl)ethyl Ester Hydrochloride |
| Chemical Name Translation | 2-哌啶乙基-4-氨基-5-氯-2-甲氧基苯甲酸酯 |
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分类
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Potent, selective 5-HT4 serotonin receptor agonist. New ester of 4-Amino-5-chloro-2-methoxybenzoic acid as potent agonist and antagonist for 5-HT4 receptors.
相关文献及参考
- [2]. D Yang, et al. New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors. J Med Chem. 1997 Feb 14;40(4):608-21.
- [3]. M Cachard-Chastel, et al. 5-HT4 receptor agonists increase sAPPα levels in the cortex and hippocampus of male C57BL/6j mice. Br J Pharmacol. 2007 Apr; 150(7): 883–892.
- Candura, S., et al.: Br. J. Pharmacol., 118, 1965 (1996),
- Cohen, M., et al.: J. Pharmacol. Exp. Ther., 254, 350 (1990),
- Yang, D., et al.: J. Med. Chem., 40, 608 (1997),
- [1]. Langlois, M., et al. Design of a potent 5-HT4 receptor agonist with nanomolar affinity. Bioorganic & Medicinal Chemistry Letters. 1994. 4(12), 1433–1436.
- [1]. Langlois, M., et al. Design of a potent 5-HT4 receptor agonist with nanomolar affinity. Bioorganic & Medicinal Chemistry Letters. 1994. 4(12), 1433–1436.
- [2]. D Yang, et al. New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists f
