PF-06840003 3-(5-氟-1H-吲哚-3-基)-2,5-吡咯烷二酮
CAS 198474-05-4 MFCD98474054
化学结构图
SMILES:
化学属性
| Mol. Formula | C12H9FN2O2 |
|---|
别名和识别编码
| Chemical Name | PF-06840003 |
|---|---|
| Chemicalbook ID | CB12523559 |
| Chemical Name Translation | 3-(5-氟-1H-吲哚-3-基)-2,5-吡咯烷二酮 |
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相关文献及参考
- [2]. Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate. J Med Chem. 2017 Dec 14;60(23):9617-9629.
- [1]. Tumang J, et al. PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune checkpoint inhibitors. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr4863.
- [1]. Tumang J, et al. PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune checkpoint inhibitors. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr4863.
- [2]. Indoleamine 2
