1-[6-(4-Chlorophenoxy)Hexyl]-3-Cyano-2-Pyridin-4-Ylguanidine 1-(6-(4-氯苯氧基)己基)-3-氰基-2-(吡啶-4-基)胍
CAS 200484-11-3 MFCD00484113
化学结构图
SMILES:
化学属性
| Mol. Formula | C19H22ClN5O |
|---|
别名和识别编码
| Chemical Name | 1-[6-(4-Chlorophenoxy)Hexyl]-3-Cyano-2-Pyridin-4-Ylguanidine |
|---|---|
| Chemical Name Translation | 1-(6-(4-氯苯氧基)己基)-3-氰基-2-(吡啶-4-基)胍 |
| Chemicalbook ID | CB41463422 |
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相关文献及参考
- [2]. Cerna D, et al. Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) activity by small molecule GMX1778 regulates reactive oxygen species (ROS)-mediated cytotoxicity in a p53- and nicotinic acid phosphoribosyltransferase1 (NAPRT1)-dependent manner. J Biol Chem. 2012 Jun 22;287(26):22408-17.
- [1]. Watson M, et al. The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Mol Cell Biol. 2009 Nov;29(21):5872-88.
- [1]. Watson M, et al. The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Mol Cell Biol. 2009 Nov;29(21):5872-88.
- [2]. Cerna D, et al. Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) activity by small molecule GMX1778 regulates reactive oxygen species (ROS)-mediated cytotoxicity in a p53- and nicotinic acid
