Zinterolhydrochloride

CAS 38241-28-0 MFCD38241280

化学结构图

38241-28-0
SMILES:

化学属性

Mol. Weight414.95
Mol. FormulaC19H26N2O4S·HCl

别名和识别编码

Chemical NameZinterol hydrochloride
Chemicalbook IDCB42276236
CAS Number38241-28-0
Synonym N-[5-[2-[(1,1-dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]-Methanesulfonamide Hydrochloride; MJ 9184 Zinterol hydrochloride
MDL NumberMFCD00867031
PubChem Substance ID329831614
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分类

  • {SNA} Adrenergics, Agonists, Bioactive Small Molecule Alphabetical Index, Neuroscience, Neurotransmission, Neurotransmitters, Z, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Skeberdis VA, et al. Beta-2 adrenergic activation of L-type Ca 2+ current in cardiac myocytes. J Pharmacol Exp Ther. 1997 Nov;283(2):452-61.
  • [3]. Desantiago J, et al. Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load. Circ Res. 2008 Jun 6;102(11):1389-97.
  • [1]. Gwee MC, et al. Pharmacological actions of a new -adrenoceptor agonist, MJ-9184-1, in anaesthetized cats. Br J Pharmacol. 1972 Nov;46(3):375-85.
  • [1]. Gwee MC, et al. Pharmacological actions of a new -adrenoceptor agonist, MJ-9184-1, in anaesthetized cats. Br J Pharmacol. 1972 Nov;46(3):375-85.
  • [2]. Skeberdis VA, et al. Beta-2 adrenergic activation of L-type Ca 2+ current in cardiac myocytes. J Pharmacol Exp Ther. 1997 Nov;283(2):452-61.
  • [3]. Desantiago J, et al. Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum

安全信息

RTECSPB0512953
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 19,626,1976

Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
WGK Germany3
GHS Symbol
Precautionary statements
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
Hazard Codes Xi
Risk Statements
  • R36 Irritating to eyes 刺激眼睛

系列性分类


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