1-Butanone,1-(2-amino-4-fluorophenyl)-4-(4-hydroxy-4-(3-(trifluoromethyl)phenyl)-1- piperidinyl)-
CAS 42048-72-6 MFCD42048726
化学结构图
SMILES:
化学属性
| Mol. Weight | 424.48 |
|---|---|
| Mol. Formula | C22H24F4N2O2 |
别名和识别编码
| Chemical Name | 1-Butanone,1-(2-amino-4-fluorophenyl)-4-(4-hydroxy-4-(3-(trifluoromethyl)phenyl)-1- piperidinyl)- |
|---|---|
| Synonym | 1-(3-(2-Amino-4-fluorobenzoyl)propyl)-4-hydroxy-4-(3-trifluoromethylphenyl)piperidine ID-4708 |
| CAS Number | 42048-72-6 |
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安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 780 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1248,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 340 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1248,1974
