BENZ(c)ACRIDINE, 11-FLUORO-7-METHYL-
CAS 439-25-8 MFCD N/A
化学结构图
SMILES: Cc1c2cccc(F)c2nc2c1ccc1ccccc12
化学属性
| Mol. Weight | 261.31 |
|---|---|
| Mol. Formula | C18H12FN |
别名和识别编码
| Chemical Name | Benz(c)acridine, 11-fluoro-7-methyl- |
|---|---|
| Chemicalbook ID | CB92373794 |
| Wiswesser Line Notation | T D6 B666 CNJ EF J1 |
| Synonym | 7-Methyl-11-fluorobenz(c)acridine 1-Fluoro-10-methyl-7,8-benzacridine |
| CAS Number | 439-25-8 |
| InChIKey | BYAVSYPENIKIBV-UHFFFAOYSA-N |
| PubChem Substance ID | 9921 |
| InChI | InChI=1S/C18H12FN/c1-11-13-7-4-8-16(19)18(13)20-17-14(11)10-9-12-5-2-3-6-15(12)17/h2-10H,1H3 |
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安全信息
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application REFERENCE : AICCA6 Acta Unio Internationalis Contra Cancrum. (Louvain, Belgium) V.1-20, 1936-64. For publisher information, see IJCNAW. Volume(issue)/page/year: 11,736,1955
TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 60 mg/kg/9W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - bronchiolar constriction REFERENCE : ACRSAJ Advances in Cancer Research. (Academic Press, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1953- Volume(issue)/page/year: 4,315,1956
