Thyroxine 4?-O-Sulfate

CAS 77074-49-8 MFCD77074498

化学结构图

77074-49-8
SMILES: N[C@@H](CC1=CC(I)=C(OC2C=C(I)C(OS(O)(=O)=O)=C(I)C=2)C(I)=C1)C(O)=O |&1:1|

化学属性

Mol. Weight856.93
Mol. FormulaC15H11I4NO7S

别名和识别编码

CAS Number77074-49-8
Chemical NameThyroxine 4?-O-Sulfate
Synonym O-[3,5-Diiodo-4-(sulfooxy)phenyl]-3,5-diiodo-L-tyrosine Thyroxine Hydrogen Sulfate Thyroxine Sulfate
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分类

  • Aromatics
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • Thyroxine 4-O-Sulfate is a metabolite and sulfoconjugated derivative of Thyroxine (T425600).

相关文献及参考

  • [2]. Rutgers M, et al. Effects of propylthiouracil on the biliary clearance of thyroxine (T4) in rats: decreased excretion of 3,5,3'-triiodothyronine glucuronide and increased excretion of 3,3',5'-triiodothyronine glucuronide and T4 sulfate. Endocrinology. 1989 Oct;125(4):2175-86.
  • [3]. Peeters RP, et al. Increased thyroxine sulfate levels in critically ill patients as a result of a decreased hepatic type Ideiodinase activity. J Clin Endocrinol Metab. 2005 Dec;90(12):6460-5.
  • Huang, W.S. et al.: Endocrine J., 44, 467 (1997); Debaveye, Y. et al.: Endocrinology, 149, 4218 (2008); Hays, M.T. et al.: Endocrine Res., 14, 51 (1988);
  • [1]. Wu SY, et al. Identification of thyroxine-sulfate (T4S) in human serum and amniotic fluid by a novel T4S radioimmunoassay. Thyroid. 1992 Summer;2(2):101-5.
  • [1]. Wu SY, et al. Identification of thyroxine-sulfate (T4S) in human serum and amniotic fluid by a novel T4S radioimmunoassay. Thyroid. 1992 Summer;2(2):101-5.
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系列性分类


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