3’-Hydroxy Repaglinide (Mixture of Diastereomers)
CAS 874908-14-2 MFCD74908142
化学结构图
SMILES: CC(C)CC(NC(=O)CC1C=CC(=C(C=1)OCC)C(O)=O)C1C=CC=CC=1N1CC(O)CCC1
化学属性
| Mol. Weight | 468.59 |
|---|---|
| Mol. Formula | C27H36N2O5 |
别名和识别编码
| CAS Number | 874908-14-2 |
|---|---|
| Chemical Name | 3’-Hydroxy Repaglinide (Mixture of Diastereomers) |
| Synonym | 2-Ethoxy-4-[2-[[1-[2-(3-hydroxy-1-piperidinyl)phenyl]-3-methylbutyl]amino]-2-oxoethyl] |
| Chemical Name Translation |
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分类
- Metabolites & Impurities
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- A metabolite of Repaglinide (R144500).
相关文献及参考
- [2]. Honkalammi J, et al. Mechanism-based inactivation of CYP2C8 by gemfibrozil occurs rapidly in humans. Clin Pharmacol Ther. 2011 Apr;89(4):579-86.
- Jarvis, B., et al.: Drugs, 59, 891 (2000),
- [1]. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probedrugs and their corresponding metabolites in human serum and urine. Anal Bioanal Chem. 2017 Jan;409(1):251-268.
- [1]. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probedrugs and their corresponding metabolites in human serum and urine. Anal Bioanal Chem. 2017 Jan;409(1):251-268.
- [2]. Honkalammi J, et al. Mechanism-based inactivation of CYP2C8 by gemfibrozil occurs rapidly in humans. Clin Pharmacol Ther. 2011 Apr;89(4):579-86.
