(S)-4-Fluoro-5-((2-Methyl-1,4-Diazepan-1-Yl)Sulfonyl)Isoquinoline Hydrochloride Dihydrate (S)-4-氟-5-((2-甲基-1,4-二氮杂卓-1-基)磺酰基)异喹啉盐酸盐二水合物

CAS 887375-67-9 MFCD87375679

化学结构图

887375-67-9
SMILES: CC1CNCCCN1S(=O)(=O)c1cccc2cncc(F)c12.Cl.O.O

别名和识别编码

Chemical Name Translation(S)-4-氟-5-((2-甲基-1,4-二氮杂卓-1-基)磺酰基)异喹啉盐酸盐二水合物
Chemical Name(S)-4-Fluoro-5-((2-Methyl-1,4-Diazepan-1-Yl)Sulfonyl)Isoquinoline Hydrochloride Dihydrate
PubChem Substance ID11625386
InChIInChI=1S/C15H18FN3O2S.ClH.2H2O/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14;;;/h2,4-5,9-11,17H,3,6-8H2,1H3;1H;2*1H2/t11-;;;/m0.../s1
Synonym Glanatec K-115 K115 compound ripasudil
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相关文献及参考

  • [2]. Kaneko Y, et al. Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm's canal endothelial cells. Sci Rep. 2016 Jan 19;6:19640.
  • [3]. Yamamoto K, et al. The novel Rho kinase (ROCK) inhibitor K-115: a new candidate drug for neuroprotective treatment in glaucoma. Invest Ophthalmol Vis Sci. 2014 Oct 2;55(11):7126-36.
  • [1]. Isobe T, et al. Effects of K-115, a rho-kinase inhibitor, on aqueous humor dynamics in rabbits. Curr Eye Res. 2014 Aug;39(8):813-22.
  • [1]. Isobe T, et al. Effects of K-115, a rho-kinase inhibitor, on aqueous humor dynamics in rabbits. Curr Eye Res. 2014 Aug;39(8):813-22.
  • [2]. Kaneko Y, et al. Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm's canal endothelial cells. Sci Rep. 2016 Jan 19;6:19640.
  • [3]. Yamamoto K, et al. The novel Rho kinase (ROCK) inhibitor K-115: a new candidate drug for neuroprotective treatment in glaucoma. Invest Ophthalmol

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