(2R,3R,4S,5R)-2-(6-(((R)-2,3-Dihydro-1H-Inden-1-Yl)Amino)-9H-Purin-9-Yl)-5-(Hydroxymethyl)Tetrahydrofuran-3,4-Diol (2R,3R,4S,5R)-2-(6-(((R)-2,3-二氢-1H-茚-1-基)氨基)-9H-嘌呤-9-基)-5-(羟甲基)四氢呋喃-3,4-二醇
CAS 96392-15-3 MFCD96392153
化学结构图
SMILES: OC[C@@H]1O[C@@H](C(O)[C@@H]1O)N1C=NC2C(N[C@H]3CCC4C=CC=CC=43)=NC=NC1=2 |&1:2,4,7,15|
化学属性
| Mol. Weight | 383.4 |
|---|---|
| Mol. Formula | C19H21N5O4 |
别名和识别编码
| CAS Number | 96392-15-3 |
|---|---|
| Chemical Name | (2R,3R,4S,5R)-2-(6-(((R)-2,3-Dihydro-1H-Inden-1-Yl)Amino)-9H-Purin-9-Yl)-5-(Hydroxymethyl)Tetrahydrofuran-3,4-Diol |
| Synonym | N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine CI 947 PD 117519 |
| Chemical Name Translation | (2R,3R,4S,5R)-2-(6-(((R)-2,3-二氢-1H-茚-1-基)氨基)-9H-嘌呤-9-基)-5-(羟甲基)四氢呋喃-3,4-二醇 |
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分类
- Carbohydrates & Derivatives
- Nucleotides
- Bases & Related Reagents
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- N6-Substituted adenosine receptor agonist; a potential antihypertensive agent.
相关文献及参考
- [2]. Tobin GA, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014 Jun;42(4):709-24.
- [3]. Enerson BE, et al. Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression. Toxicol Pathol. 2006;34(1):27-32.
- Daly, J., et al.: Biochem. Pharmacol., 43, 1089 (1992),
- [1]. Reynolds DL, et al. Liquid chromatographic analysis of the adenosine agonist PD 117519 in dog plasma. J Pharm Biomed Anal. 1991;9(4):345-9.
- [1]. Reynolds DL, et al. Liquid chromatographic analysis of the adenosine agonist PD 117519 in dog plasma. J Pharm Biomed Anal. 1991;9(4):345-9.
- [2]. Tobin GA, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014 Jun;42(4):709-24.
- [3]. Enerson BE, et al. Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression. Toxicol Pathol. 2006;34(1):27-32.
