Ethyl 3-chloro-3-oxopropanoate 氯甲酰乙酸乙酯
CAS 36239-09-5 MFCD00000736
化学结构图
SMILES: CCOC(=O)CC(=O)Cl
化学属性
| Mol. Formula | C5H7ClO3 |
|---|---|
| Mol. Weight | 151 |
| Refractive index | 1.4270 to 1.4310 |
| Boiling Point | 83°C/22mmHg(lit.) |
| Density | 1.176 |
| Flash Point | 64°C(lit.) |
| TSCA | No |
| Appearance | 无色或淡黄色液体，密度 1.17，沸点 79-80℃(25mmHg)，折射率 1.425-1.431，闪点 67℃，与水起反应 |
| Stability | 对水分敏感 |
别名和识别编码
| Chemical Name | Ethyl 3-chloro-3-oxopropanoate |
|---|---|
| Synonym | ETHYL 3-CHLORO-3-OXOPROPIONATE,TECH AURORA KA-3051 MALONIC ACID MONOETHYL ESTER CHLORIDE Ethylmalonylchloride,95% 乙基-3-氯-3-氧丙酸酯 丙二酸单乙酯酰氯 Ethyl Maloriyl Chloride 乙基丙二酰氯 ETHYL 2-(CHLOROCARBONYL)ACETATE Ethyl (chloroformyl)acetate, Ethyl 3-chloro-3-oxopropionate 氯甲酰乙酸乙酯 |
| PubChem Substance ID | 87569735 |
| EC Number | 252-934-5 |
| Beilstein Registry Number | 2(4)1887 |
| MDL Number | MFCD00000736 |
| CAS Number | 36239-09-5 |
| Alfabeta Name | ETHYLMALONYLCHLORIDE |
| Chemical Name Translation | 氯甲酰乙酸乙酯 |
| Reaxys-RN | 636215 |
| InChIKey | KWFADUNOPOSMIJ-UHFFFAOYSA-N |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Acid Halides, Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks
产品应用
- 多功能的炔丙基醇，肼，和胺的酰化剂。
- 用于通过与炔丙胺进行酰胺化反应，然后进行碱催化 5-外型-对角系环加成合成 3-吡咯啉-2-酮
相关文献及参考
- Useful synthetic building block, e.g. in an oxazole synthesis: J. Med. Chem., 36, 3871 (1993):
- Formation of amides has been used in the syntheses of 1,2,4-triazine-3,6-diones, and of a vicinal tricarbonyl amide derivative of L-phenylalanine: J. Org. Chem., 60, 5992 (1995); 61, 1872 (1996).
安全信息
GHS Symbol
- H227 Combustible liquid 可燃液体
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338+P310
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P301+P330+P331+P310
- P370+P378
- P304+P340
- P304+P340+P310
- P403+P235
- P390 Absorb spillage to prevent material damage. 吸收溢出物，防止重大损害。
- P301+P330+P331
- P303+P361+P353+P310+P363
- P405 Store locked up. 上锁保管。
- P234 Keep only in original container. 只保留在原来的容器中。
- P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
- R14 Reacts violently with water 遇水会猛烈反应
- R34 Causes burns 会导致灼伤
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S7 Keep container tightly closed 保存在严格密闭容器中；
其他信息
- Sigma Aldrich:36239-09-5(sigmaaldrich)
