1,2-Dichloroethane 1,2-二氯乙烷

CAS 107-06-2 MFCD00000963

化学结构图

107-06-2
SMILES: ClCCCl

化学属性

Refractive index1.4420 to 1.4470
Boiling Point83
Melting Point-35
Flash Point17°C(lit.)
TSCAYes
Autoignition Point775 °F
Vapor Density3.4 (20 °C, vs air)
Vapor Pressure87 mmHg ( 25 °C)
Solubility微溶于水,可混溶于醇、醚、氯仿。
Stability对光敏感
Density1.256
Mol. FormulaC2H4Cl2
Mol. Weight99.00
Danger-Level甲类

别名和识别编码

Chemical Name1,2-Dichloroethane
Synonym 1 1,2-DCE 1,2-Dichloorethaan 1,2-Dichlorethane 1,2-Dichloroethane 1,2-Dichloräthan (Tieftemperaturmodifkation) 1,2-Ethylene dichloride 1,2-dichloroethane,anhydrous 1,2-二氯乙烷, 99+% 1,2-二氯乙烷, HPLC GRADE, 99% MIN 1,2-二氯乙烷;对称二氯乙烷;乙撑二氯;二氯化乙烯;二氯乙烷 2-二氯乙烷 Aethylenchlorid Chloru Destruxol borer-sol Dutch liquid EDCEthylene chloride ENT 1,656 ETHYLENE CHLORIDE Ethylendichlorid Ethylene Chloride, Ethylene Dichloride Ethylene chloride Ethylene chloride, Ethylene dichloride NCI-C00511 freon 150 {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {ALD Äthylenchlorid 二氯化乙烯 二氯化乙烯;氯化乙烯;EDC 二氯化乙烯,二氯乙烷 对称二氯乙烷
CAS Number107-06-2
PubChem Substance ID11
EC Number203-458-1
Beilstein Registry Number605264
MDL NumberMFCD00000963
Reaxys-RN605264
Merck Number3797
Chemical Name Translation1,2-二氯乙烷
Wiswesser Line NotationG2G
LabNetwork Molecule IDLN00164820
InChIInChI=1S/C2H4Cl2/c3-1-2-4/h1-2H2
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分类

  • {SNA} Additiona
  • {SNA} Anhydrous, Anhydrous Solvents, Returnable Containers, Solvent Bottles, Solvent Packaging Options, Solvent Products Available in Returnable Containers, Solvent by Application, Solvents, Sure/Seal Bottles
  • Anhydrous, Anhydrous Solvents, Products, Returnable Containers, Solvent Bottles, Solvent Packaging Options, Solvent by Application, Solvents, Sure/Seal Bottles
  • {uni_hamburg} no charge; 1fragment
  • {SNA} ACS Grade Solvents, ACS and Reagent Grade Solvents, Analytical Reagents, Analytical Reagents for General Use,
  • {SNA} Additional Standards,
  • {SNA} Alpha Sort, Analytical Standards, Chromatography,
  • {SNA} ACS Grade Solvents,

产品应用

  • 有机合成,萃取剂,油类、脂肪、树胶、树脂等的极好溶剂,分析硼,制造乙酰纤维,烟草萃取剂。

相关文献及参考

  • Short: II/25B
  • Merck:14,3797
  • Short: II/2
  • Merck:14,3797 Beilstein:1,84

安全信息

GHS Symbol
WGK Germany3
Hazard Codes 3 F,T F;T
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H302 Harmful if swallowed 吞食有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H350 May cause cancer 可能致癌
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H331 Toxic if inhaled 吸入中毒
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSKI0525000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310+P331+P330
  • P302+P352+P332+P313+P362+P364
  • P304+P340+P311
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P311
  • P308+P313
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S24 Avoid contact with skin 避免皮肤接触;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • S7 Keep container tightly closed 保存在严格密闭容器中;
Risk Statements
  • R1 Explosive when dry 干燥时易爆
  • R11 Highly flammable 非常易燃
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R45 May cause cancer 可能致癌
UN Number 1184 UN 1184 3/PG 2
Packing GroupII
Storage condition 密封避光保存 密封保存 密封避光保存。 0-6°C
Hazard Class3/6.1
Warnings 危化品目录(2015)
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 18 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Vascular - tumors
   Gastrointestinal - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-55,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Skin and Appendages - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-55,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1120 gm/kg/74W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appendages - tumors
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 63,1433,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 38 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Vascular - tumors
   Gastrointestinal - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report

TYPE OF TEST            : TCLo - Lowes

{haz

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - general anesthetic
   Behavioral - ataxia
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 48A,91,1970

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   7,205,1934

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 286 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from stomach
   Gastrointestinal - nausea or vomiting
   Liver - fatty liver degeneration
REFERENCE :
   CLCEAL Casopis Lekaru Ceskych. Journal of Czech Physicians.

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - general anesthetic
   Behavioral - ataxia
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 48A,91,1970

TYPE OF TEST            : LCLo - Lowest published lethal concentration

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 2 ppm/96H (Continuous)
REFERENCE :
   EVSRBT Environmental Science Research.  (Plenum Pub. Corp., 233 Spring St.,
   New York, NY 10013) V.1-    1972-  Volume(issue)/page/year: 32,65,1985

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 40 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 90,183,1981

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 2000 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 201,401,1988

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  V

TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 150 mg/kg
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St.,

TYPE OF TEST            : Body fluid assay
TEST SYSTEM             : Rodent - mouse Bacteria - Salmonella typhimurium
DOSE/DURATION           : 80 mg/kg
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   24,265,1979

TYPE OF

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 300 ppm/7H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   BANRDU Banbury Report.  (Cold Spring Harbor Laboratory, POB 100, Cold Spring
   Harbor, NY 11724) V.1-    1979-  Volume(issue)/page/year: 5,149,1980

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 208 mg/m3/6H
SEX/DURATION            : female 2 week(s) pre-mating
                          female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   CHYCDW Zhonghua Yufangyixue Zazhi.  Chinese Journal of Preventive Medicine.
   (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep.
   China)  Beginning history not known.  Volume(issue)/page/year: 23,199,1989

Restrict 危险品

其他信息

  • 下游产品:多效唑 --> 3-氨基-5-氟吡啶 --> S-(-)-1,1'-联萘-2,2'-双二苯膦 --> (5-氯-1-苯并噻吩-3-基)甲醇 --> (5-溴-3-苯并[B]噻吩)甲醇 --> O-6-苄基鸟嘌呤 --> 乙酰甲胺磷 --> 三乙烯四胺 --> 1,2-双(二苯基膦)乙烷氯化镍 --> 5-氯苯并[B]噻吩-3-羧酸 --> 5-溴苯并[B]噻吩-3-甲酸 --> 吡咯-2-羧酸 --> 1-叔丁氧羰基-4-甲氨基哌啶 --> 3-(2-噻吩基)-5-氨基异噁唑 --> 1-乙酰基萘 --> 7-羟基异黄酮 --> 1-(5-溴-1-苯并噻吩-3-基)乙酮 --> 3-乙酰硫茚 --> 2-三氟甲基-喹啉-7-羧酸 --> 新型聚丙烯基磺酸型阳离子交换膜 --> 氯乙烯 --> 1,5-二氮杂双环[4.3.0]壬-5-烯 --> 三(2-氨基乙基)胺 --> 4-溴-1-氯异喹啉 --> 达唑氧苯 --> 3-氨基-4-甲氧基吡啶 --> N-乙酰基哌啶-4-酰氯 --> 硝基环己烷 --> 乙酸甲酯环己酯 --> 1,1,2-三氯乙烷 --> 2-(2,6-二氯苯氧基)乙基肼 --> 氯乙酰异氰酸酯 --> 1,1-二氯乙烷
  • 方法三:1.乙烯与氯气直接合成法 以乙烯和氯气在1,2-二氯乙烷介质中进行氯化生成粗二氯乙烷及少量多氯化物,加碱闪蒸除去酸性物及部分高沸物,用水洗涤至中性,共沸脱水,精馏,得成品。2.乙烯氧氯化法乙烯
  • 可燃性危险特性:遇明火、高温、氧化剂易燃; 燃烧产生有毒氯化物烟雾
  • 图谱信息:1,2-二氯乙烷(107-06-2)红外图谱(IR1) 1,2-二氯乙烷(107-06-2)Raman光谱 1,2-二氯乙烷(107-06-2)核磁图( 1 HNMR) 1,2-二氯乙烷(107-06-2)核磁图( 13 CNMR) 1,2-二氯乙烷(107-06-2)质谱(MS
  • {Chem
  • 食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称 允许使用该种添加剂的食品中文名称 添加剂功能 最大允许使用量(g/kg) 最大允许残留量(g/kg) 1,2-二氯乙烷 食品 食品工业用加工助剂 / 食品工业用加工助剂一般
  • 上游原料:乙醇 --> 盐酸 --> 氯 --> 三氯化磷 --> 曙光红(四溴荧光素) --> 酸性氧化铝 --> 2-氯乙醇 --> 三氯乙醛 --> 乙烯 --> 金属催化剂 --> 石油裂解气
  • 方法一:其制备方法是将乙烯和氯气同时鼓泡通入充有二氯乙烷的氯化器中,乙烯被氯化生成1,2-二氯乙烷,反应过程中应进行冷却,生成的二氯乙烷用碱液中和至中性,分层、精馏即得成品。反应方程式如图: CH 2 =CH 2 +Cl 2 [(32±2)℃]→CH 2 Cl—CH 2 Cl
  • 方法二:由氯与乙烯在金属催化剂存在下反应,然后蒸馏而得。
  • 职业标准:TWA 40 毫克/ 立方米; STEL 80 毫克/ 立方米
  • 用途四:主要用于制造氯乙烯、乙二酸和乙二胺,还可作溶剂、谷物熏蒸剂、洗涤剂、萃取剂、金属脱油剂等
  • 1,2-二氯乙烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/
  • 毒性分级:高毒
  • 参考质量标准:FCC,1996 酸度(以盐酸计) ≤10mg/kg 馏程 82~85℃ 游离卤素试验 阴性 重金属 ≤1mg/kg 不挥发残渣 ≤0.002% 相对密度(d 25 25 ) 1.245~1.255 水分(GT-32-1) ≤0.03%
  • 用途六:1,2-二氯乙烷是杀菌剂稻瘟灵和植物生长调节剂矮壮素的中间体。
  • 图谱信息:1,2-二氯乙烷(107-06-2)红外图谱(IR1) 1,2-二氯乙烷(107-06-2)Raman光谱 1,2-二氯乙烷(107-06-2)核磁图( 1 HNMR) 1,2-二氯乙烷(107-06-2)核磁图( 13 CNMR) 1,2-二氯乙烷(107-06-2)质谱(MS) 1,2-二氯乙烷(107-06-2)红外图谱(IR2)
  • F:3-10
  • 挥发性有机化合物(VOCs)单组分标准液
  • 易燃,有似氯仿的甜味,能与乙醇、氯仿

系列性分类


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