Butyl nitrite 亚硝酸丁酯

CAS 544-16-1 MFCD00002058

化学结构图

544-16-1
SMILES: CCCCON=O

化学属性

Mol. FormulaC4H9NO2
Mol. Weight103
Refractive index1.3750 to 1.3790
Boiling Point78
Density0.882
Flash Point-13°(9°F)
TSCAYes
Vapor Pressure760 mmHg ( 78 °C)
Solubility略溶于水

别名和识别编码

Chemical NameButyl nitrite
CAS Number544-16-1
PubChem Substance ID10996
EC Number208-862-1
Beilstein Registry Number1701036
MDL NumberMFCD00002058
Synonym 1-Nitrosooxy-butane 1-butyl nitrite 1-butylnitrite BUTYL NITRITE Butyl ester of nitrous acid Butyl nitrite N-BUTYL NITRITE N-Butylnitrite, 95%, stabilized N-Butynitrite N-butyl nitrate NBN NCI-C56553 NCL-C-56553 NITROUS ACID BUTYL ESTER Nitriloniobium(III) Nitrous acid butyl Nitrous acid butyl ester Nitrous acid, butyl ester Nitrous acid, n-butyl ester Salpetrigsäurebutylester butyl nitrite butylnitrites n-Butyl nitrite n-Butylnitrit n-Butylnitrite n-Butylnitrite, stabilized, 95% n-C4H9ONO n-butyl nitrite n-butyl nitrite, 15N-labeled nitrous aci
Reaxys-RN1701036
Merck Number1582
Chemical Name Translation亚硝酸丁酯
Wiswesser Line NotationONO4
LabNetwork Molecule IDLN00009188
InChIInChI=1S/C4H9NO2/c1-2-3-4-7-5-6/h2-4H2,1H3
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分类

  • {SA} Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Organic Nitrates/Nitrites
  • Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Organic Nitrates/Nitrites
  • {uni_hamburg} no charge; 1fragment

相关文献及参考

  • Merck 14 ,1582
  • Beil. 1 ,IV,1523
  • Fieser 1 ,97
  • Corp MSDS 1 (1), 642:D / FT-NMR 1 (1), 621:A / RegBook 1 (1), 429:D / Sax 6 , 591 / Structure Index 1 , 63:B:1 / Vapor Phase 3 , 479:A
  • Short: II/19b Title: Molecular Constants: Rotational, Centrifugal Distortion and Related Constants of Diamagnetic Asymmetric Top Molecules Author: Demaison, J.; Hüttner, W.; Vogt, J.; Wlodarczak, G. Editor: Hüttner, W. Source: Landolt-Börnstein, New Series Volume: II/19b Year: 1992 Keyword: organic compounds; molecular constants; spectroscopy; microwave spectroscopy ISBN: 3-540-54578-6 ISBN: 978-3-540-54578-1 Internet Resource: DOI:10.1007/b44334 RefComment: XI, 488 pages. Abstract: Volume II/19 Molecular Constants mostly from Microwave, Molecular Beam and Sub-Doppler Laser Spectroscopy is a supplement to the earlier volumes II/4, II/6, and II/14. The slight change in the title reflects current trends in the applications of spectroscopic methods. Together, the four volumes collect all the critically evaluated data published up to 1989/90 on constants of free molecules obtained by classical and modern spectroscopy. Volume II/19 is divided into four parts to record the growing number of investigations, especially in the microwave and millimeter wave regions, where modern techniques like Fourier Transform Microwave Spectroscopy have made new objects of interest such as molecular complexes and clusters accessible to study. Subvolume II/19b contains corresponding data on diamagnetic asymmetric top molecules.
  • Short: III/35B Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts and Coupling Constants for Fluorine-19 and Nitrogen-15 Author: Balasubramanian, M.; Gupta, R.R.; Jain, M.; Perumal, S. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35B Year: 1998 ISBN: 3-540-63275-1 ISBN: 978-3-540-63275-7 Internet Resource: DOI:10.1007

安全信息

GHS Symbol
WGK Germany1
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H301 Toxic if swallowed 吞食有毒
  • H301+H331
  • H331 Toxic if inhaled 吸入中毒
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 3 F,T F;T
RTECSRA0780000
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P303+P361+P353
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
  • P320 Specific treatment is urgent (see … on this label). 紧急具体治疗(见本标签上的)。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P370+P378
  • P403+P233
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
UN Number 2351
Storage condition 0-10 储存温度2-8°C 0-10°C 0-6°C
Risk Statements
  • R11 Highly flammable 非常易燃
  • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R8 Contact with combustible material may cause fire 遇到易燃物会导致起火
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S24 Avoid contact with skin 避免皮肤接触;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Packing GroupII
Hazard Class3
Warnings 危化品目录(2015)
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 158 mg/kg
TOXIC EFFECTS :
   Liver - other changes
REFERENCE :
   RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD
   Pub. Ltd., P.O. Box 966, Westbury, NY 11590)  V.1-    1970-
   Volume(issue)/page/year: 26,75,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 171 mg/kg
TOXIC EFFECTS :
   Liver - other changes
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   RCSADO Research Communications in Substances Abuse.  (PJD Pub. Ltd., P.O.Box
   966, Westbury, NY 11590) V.1-    1980-  Volume(issue)/page/year: 3,233,1982

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 567 ppm/1H
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - cyanosis
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   1,448,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 83 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - rigidity (including catalepsy)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JJATDK JAT, Journal of Applied Toxicology.  (John Wiley & Sons Ltd., Baffins
   Lane, Chichester, W. Sussex PO19 1UD, UK)  V.1-    1981-
   Volume(issue)/page/year: 1,30,1981

TYPE OF TEST            : LC50

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   BSIBAC Bolletino della Societe Italiana di Biologia Sperimentale.  (Casa
   Editrice Idelson, Via A. de Gasperi, 55, 80133 Naples, Italy)  V.2- 1927- 
   Volume(issue)/page/year: 56,816,1980

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 2820 umol/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   14,115,1989

Restrict 危险品

其他信息

  • 亚硝酸丁酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 N0376 亚硝酸丁酯 Butyl Nitrite 500ML 3040元 2014/06/02 N0376 亚硝酸丁酯 Butyl Nitrite 25ML 371元 2010/06/21 298861000 亚硝酸丁酯 n-Butylnitrite 95%, stabilized 100 GR 1178元
  • MSDS 信息:亚硝酸正丁酯(544-16-1).msds
  • 用途一:用于有机合成。
  • 毒性分级:高毒
  • 下游产品:4-氨基水杨酸 --> 4-叔丁氧羰基-2-甲基哌嗪 --> 2-氨基-5-羟基吡啶 --> 氯辛硫磷 --> 硫酸长春地辛 --> 新铜铁灵 --> 铜铁试剂
  • Acros Organics:亚硝酸正丁酯 n-Butylnitrite, stabilized, 95%(544-16-1)
  • MOL 文件:544-16-1.mol
  • 可燃性危险特性:遇明火、高温、氧化剂易燃; 燃烧产生有毒氮氧化物烟雾;遇光产生有毒氧化氮气体
  • 灭火剂:干粉、二氧化碳、泡沫
  • 储运特性:库房通风低温干燥; 与氧化剂、酸类分开存放
  • TCI Shanghai:亚硝酸丁酯 Butyl Nitrite,>;90.0%(GC)(544-16-1)
  • 蒸气压:760 mm Hg ( 78 °C)
  • 急性毒性:口服- 大鼠 LD50: 83 毫克/ 公斤; 口服- 小鼠 LD50: 171 毫克/ 公斤
  • 图谱信息:亚硝酸丁酯(544-16-1)质谱(MS) 亚硝酸丁酯(544-16-1)核磁图( 13 CNMR) 亚硝酸丁酯(544-16-1)核磁图( 1 HNMR) 亚硝酸丁酯(544-16-1)红外图谱(IR1)
  • F:8-10-23
  • Sigma Aldrich:544-16-1(sigmaaldrich)
  • 方法一:由丁醇与亚硝酸钠反应而得。
  • 职业标准:STEL 1 毫克/ 立方米
  • 外观性质:无色或浅黄色油状液体,有特殊气味。
  • 类别:易燃液体

系列性分类


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