Ethyl 3,4-Dihydroxybenzoate 3,4-二羟基苯甲酸乙酯
CAS 3943-89-3 MFCD00002199
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Building Blocks,
- {SNA} Aerobic Glycolysis (the Warburg Effect), Building Blocks, C8 to C9, Cancer Metabolism, Cancer Research, Carbonyl Compounds, Cell Biology, Chemical Synthesis, Esters, HIF Prolyl-Hydroxylase Inhibitors, Inhibitors of Aerobic Glycolysis (the Warburg Effect), Organic Building
产品应用
- An antioxidant
相关文献及参考
- [2]. Sebastian Philipp, et al. Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS. Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H450-7.
- [3]. Byeong-Ju Kwon, et al. Ethyl-3,4-dihydroxybenzoate with a dual function of induction of osteogenic differentiation and inhibition of osteoclast differentiation for bone tissue engineering. Tissue Eng Part A. 2014 Nov;20(21-22):2975-84.
- [4]. D Nandan, et al. Ethyl-3,4-dihydroxybenzoate inhibits myoblast differentiation: evidence for an essential role of collagen. J Cell Biol. 1990 May;110(5):1673-9.
- Rayman, M., et al.: Lancet, 356, 233 (2000),
- Stadlober, M., et al.: Food Chem., 73, 357 (2001),
- [1]. Bo Han, et al. A prolyl-hydroxylase inhibitor, ethyl-3,4-dihydroxybenzoate, induces cell autophagy and apoptosis in esophageal squamous cell carcinoma cells via up-regulation of BNIP3 and N-myc downstream-regulated gene-1. PLoS One. 2014
安全信息
GHS Symbol
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352
- P302+P352+P332+P313+P362+P364
- P304+P340
- P305+P351+P338
- P305+P351+P338+P337+P313
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P332+P313
- P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
其他信息
- 参考质量标准:FAO/WHO,1992 氯化有机物(以c1计) ≤100mg/kg 游离酸(以原儿茶酸计) ≤0.5% 安全数据 回目录 【危险品标志 】 Xi 【危险类别码 】 R36/37/
- 用途二:抗氧化剂。
- 方法一:由3,4一二羟基苯甲酸与乙醇酯化而得。
- Acros Organics:3,4-二羟基苯甲酸乙酯 Ethyl 3,4-dihydroxybenzoate, 97%(3943-89-3)
- Ethyl 3,4-Dihydroxybenzoate is an antioxidant compound. It also exhibits anti-inflammatory, anti-parasitic, antibacterial, anti-metastatic, and anticancer activities. Protocatechuic acid inhibits TNF-induced expression and release of adhesion molecules and pro-inflammatory cytokines as well as ADP-induced expression of platelet P-selectin. This compound increases quinone reductase activity and acts as a radical scavenger. Protocatechuic acid ethyl ester inhibits RhoB activation, decreasing expression of matrix metalloproteinase 2 (MMP2) and inactivating NF-κB and also inhibits human topoisomerase II.
- MOL 文件:3943-89-3.mol
- 3,4-二羟基苯甲酸乙酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0571 3,4-二羟基苯甲酸乙酯 Ethyl 3,4-Dihydroxybenzoate 5G 240元 2014/06/02 D0571 3,4-二羟基苯甲酸乙酯 Ethyl 3,4-Dihydroxybenzoate 25G 684元 2010/06/21 325810250 3,4-二羟基苯甲酸乙酯 Ethyl 3,4-dihydroxybenzoate 9
- 鉴别试验:溶解性 不溶于水;溶于乙醇(0T-42)。 熔程132~135℃。按常规方法测定。 取试样0.5g溶于l0ml氢氧化钠试液(TS-224)后蒸馏。取澄清初馏液4ml,加等体积的氢氧化钠试液和2~3滴碘试液(TS-124),加热此溶液,应有碘仿气味释出。 取试样0.1g溶于5ml乙醇,加1滴稀氯化铁试液(TS-103),应呈绿色。 将试验3中的蒸馏残留物酸化,将沉淀重结晶,其熔程为190~194℃(同时分解)。
- 参考质量标准:FAO/WHO,1992 氯化有机物(以c1计) ≤100mg/kg 游离酸(以原儿茶酸计) ≤0.5% 安全数据 回目录 【危险品标志 】 Xi 【危险类别码 】 R36/37/38 【安全说明 】 S26-S36-S37/39 【WGK Germany 】 3 【Hazard Note 】 Irritant 制备方法 回目录 【方法一】 由3,4一二羟基苯甲酸与乙醇酯化而得。 上下游产品信息 回目录 【上游原料】 苯甲酸 化学品安全说明书(MSDS) 回目录 【MSDS 信息】 Ethyl 3,4-dihydroxybenzoate(3943-89-3).msds 常见问题列表 回目录 【鉴别试验】 溶解性 不溶于水;溶于乙醇(0T-42)。 熔程132~135℃。按常规方法测定。 取试样0.5g溶于l0ml氢氧化钠试液(TS-224)后蒸馏。取澄清初馏液4ml,加等体积的氢氧化钠试液和2~3滴碘试液(TS-124),加热此溶液,应有碘仿气味释出。 取试样0.1g溶于5ml乙醇,加1滴稀氯化铁试液(TS-103),应呈绿色。 将试验3中的蒸馏残留物酸化,将沉淀重结晶,其熔程为190~194℃(同时分解)。 知名试剂公司产品信息 回目录 【Acros Organics】 3,4-二羟基苯甲酸乙酯 Ethyl 3,4-dihy