2',4'-Dihydroxyacetophenone 2,4-二羟基苯乙酮
CAS 89-84-9 MFCD00002279
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Aromatics
- {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; ketone; alcohol; 1fragment
- Miscellaneous Reagents
- {SNA} Building Blocks, C7 to C8, Carbonyl Compounds, Chemical Synthesis, Ketones, Organic Building Blocks
产品应用
- 用作有机合成中间体。医药工业用于制冠心病药乙氧黄酮等。
相关文献及参考
- Merck: 14,8140
- Merck: 14,8140 Beilstein:8,266
- Short: EINECS
- Short: III/35E
- Short: III/38B
- The position of O-alkylation can be varied by suitable choice of reagent. Thus, NaH in DMSO followed by MeI gives predominantly the 2-alkylated product, whereas Li2CO3 in DMF favors 4-alkylation. The latter is a fairly general method for the alkylation of phenols, thiophenols and ß-diketones with pKa less than about 8: Synth. Commun., 18, 1379 (1988).
- [1]. Li XJ, et al. Bioactive metabolites from biotransformation of paeonol by the white-rot basidiomycete Coriolus versicolor. Nat Prod Commun. 2011 Aug;6(8):1129-30.
安全信息
GHS Symbol
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P350
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P310
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P332+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- H315 Causes skin irritation 会刺激皮肤
- H318 Causes serious eye damage 严重伤害眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H303 May be harmfully swallowed 吞食可能有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2830 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological Series, Bulletin. (Pittsburgh, PA) 1947-69. Volume(issue)/page/year: 6,1,1967
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 20 mg/kg SEX/DURATION : female 4 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : JSICAZ Journal of Scientific and Industrial Research, Section C: Biological Sciences. (New Delhi, India) V.14-21, 1955-62. For publisher information, see IJEBA6. Volume(issue)/page/year: 19,264,1960
其他信息
- MOL 文件:89-84-9.mol
- TCI Shanghai:2',4'-二羟基苯乙酮 2',4'-Dihydroxyacetophenone,>;98.0%(GC)(T)(89-84-9)
- 海关编码:29145000
- Sigma Aldrich:89-84-9(sigmaaldrich)
- Acros Organics:2',4'-二羟基苯乙酮 2',4'-Dihydroxyacetophenone, 98%(89-84-9)
- 下游产品:7-羟基香豆素 --> 1-[4-(苯甲酰氧基)-2-羟基苯基]-3-苯基-1,3-丙二酮 --> 1-[2,4-双(苯甲酰氧基)苯基]乙酮 --> 7-羟基黄酮
- 图谱信息:2,4-二羟基苯乙酮(89-84-9)质谱(MS) 2,4-二羟基苯乙酮(89-84-9)红外图谱(IR1) 2,4-二羟基苯乙酮(89-84-9)核磁图( 1 HNMR)
- Alfa Aesar:2',4'-二羟基苯乙酮,98% 2',4'-Dihydroxyacetophenone, 98%(89-84-9)
- Hazard Note:Irritant
- 用途一:用作有机合成中间体。医药工业用于制冠心病药乙氧黄酮等。
- 上游原料:氯化锌 --> 间苯
- MSDS 信息:Resacetophenone(89-84-9).msds
- 方法一:由间苯二酚与乙酸乙酰化而得。此外,由间苯二酚与氯乙酰或乙酐在氯化锌存在下反应,也可制得该品。
- 敏感性:Moisture Sensitive
- 在水中渐渐分解。溶于热醇、吡啶及冰醋酸中,几乎不溶于醚、苯和氯仿。与氯化铁作用显红色。
- 2,4-二羟基苯乙酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0561 2',4'-二羟基苯乙酮 2',4'-Dihydroxyacetophenone 25G 258元 2014/06/02 D0561 2',4'-二羟基苯乙酮 2',4'-Dihydroxyacetophenone 500G 2230元 2010/06/21 114801000 2,4-二羟基苯乙酮 2',4'-Dihydroxyacetophenone 98% 100 GR 810元