Bromoacetic Acid 溴乙酸
CAS 79-08-3 MFCD00002678
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资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
一流品牌服务
分类
- {SNA} A-B, Alpha Sort, Analytical Standards, Analytical/Chromatography, Applications, B, Bioactive Small Molecules, Bromo, Cell Biology, Chemical Class, Chromatography, Disinfection Byproducts, Disinfection Product Residues and Solvents, Environmental Standards, Food & Beverage Analysis, Halogenated, Processing/Packaging Contaminants, Volatiles/ Semivolatiles, Waste water
- 500 Series Drinking Water Methods, Analytical Standards, Analytical/Chromatography, Bromo, Chemical Class, EPA,
- {SNA} Acids,
产品应用
- 用于有机合成。
相关文献及参考
- Short: II/27B
- Reaction with a dialkyl phosphite followed by an aldehyde has been used in a convenient one-pot synthesis of acrylic acids: J. Org. Chem., 46, 2514 (1981). For examples with reaction schemes, see Chloroacetic acid, A11482 and 2-Bromopropionic acid, A17569.
- Short: II/14a
- Merck: 14,1400
- Merck: 14,1400 Beilstein:2,213
安全信息
- H290 May be corrosive to metals 可能腐蚀金属。
- H315 Causes skin irritation 会刺激皮肤
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H331 Toxic if inhaled 吸入中毒
- H311 Toxic in contact with skin 皮肤接触中毒
- H301 Toxic if swallowed 吞食有毒
- H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
GHS Symbol
- S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
- R35 Causes severe burns 会导致严重灼伤
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
- R50 Very toxic to aquatic organisms 对水生生物极毒
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
- P234 Keep only in original container. 只保留在原来的容器中。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310
- P301+P330+P331+P310
- P303+P361+P353
- P303+P361+P353+P310+P363
- P304+P340+P310
- P305+P351+P338
- P305+P351+P338+P310
- P308+P313
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P390 Absorb spillage to prevent material damage. 吸收溢出物,防止重大损害。
- P403+P233
- P501 Dispose of contents/container to..… 处理内容物/容器.....
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - rigidity (including catalepsy) REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555280
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0191-1149S
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >48 mg/kg TOXIC EFFECTS : Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher i
TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 114 gm/m3/30M TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 41,113,1978
TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - mouse Leukocyte DOSE/DURATION : 100 umol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 30,1497,1981
其他信息
- 用途二:溴乙酸是制备ω-溴-2,4-二氯苯乙酮的原料,后者是制备抑霉唑、丙环唑等三唑类杀菌剂的中间体。
- 外观性质:无色结晶,易潮解。
- F:3-19-23
- Acros Organics:溴乙酸 Bromoacetic acid in ethyleneglycol, ca. 10% BrCH2CO2H, 35% glycol balance ester(79-08-3)
- Sigma Aldrich:79-08-3(sigmaaldrich)
- 用途三:有机合成中间体。用于农药和医药的生产中。还可生产其酯类。
- 下游产品:溴乙酸乙酯 --> 苯并噻吩 --> 3-羧甲基绕丹宁 --> 7-羟基-4-甲基香豆素-3-乙酸 --> 2-甲基巯基嘧啶-5-甲醛 --> 2-乙基-5-嘧啶甲醛 --> 2-甲氧基-5-醛基嘧啶 --> 2-氨基-5-嘧啶甲醛 --> 溴乙酸甲酯 --> 齐拉西酮 --> 七氟烷 --> 2-(1-吡咯烷基)乙酸 --> 溴乙酰氯
- MSDS 信息:溴乙酸(79-08-3).msds
- 方法二:1.以醋酸为原料,在吡啶存在下滴加溴素进行反应制取之。2.由氯乙酸与氢溴酸反应而得。3.由羟乙酸与氢溴酸反应而得。
- 急性毒性:腹注- 大鼠 LD50: 50 毫克/ 公斤; 口服- 小鼠 LD50: 100 毫克/ 公斤
- 储运特性:库房通风低温干燥; 与氧化剂、碱类分开存放。
- 上游原料:溴 --> 乙酐
- 可燃性危险特性:可燃; 加热排放有毒溴化物烟雾
- 易吸湿潮解。易溶于水、丙酮和乙醇,溶于乙醚,实际上不溶于正庚烷。溶解度:900 g/100ml 水(25°C),900g/100g甲醇(25°C), ether-900g/100g醚, benzene-308g/100g苯,168g/100g四氯化碳。
- Hazard Note:Toxic/Corrosive
- 类别:腐蚀物品
- 方法一:在乙酐和无水乙酸的混合物中以吡啶作溶剂与溴作用而得。反应方程式:CH 3 COOH+Br 2 →BrCH 2 COOH+HBr
- MOL 文件:79-08-3.mol
- 图谱信息:溴乙酸(79-08-3)红外图谱(IR3) 溴乙酸(79-08-3)红外图谱(IR1) 溴乙酸(79-08-3)Raman光谱 溴乙酸(79-08-3)红外图谱(IR2)
- TCI Shanghai:溴乙酸 Bromoacetic Acid,>;98.0%(T)(79-08-3)
- 用途一:用于有机合成
- 灭火剂:砂土、泡沫、雾状水、二氧化碳
- 毒性分级:高毒
- 溴乙酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80019026 溴乙酸;溴代乙酸;一溴乙酸;溴醋酸 100g 165.5元 2011/04/16 B0531 溴乙酸 Bromoacetic Acid 25G 185元 2011/04/16 B0531 溴乙酸 Bromoacetic Acid 500G 930元
- Alfa Aesar:溴乙酸,98+% Bromoacetic acid, 98+%(79-08-3)