2-Methylfuran 2-甲基呋喃
CAS 534-22-5 MFCD00003248
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Alphabetical Listings, Flavors and Fragrances, Halal Certified Products, I - N, I-N, Kosher Certified Products,
- {SNA} Alcoholic & Nonalcoholic Beverages,
- {Chemicalbook} 农药中间体: 杀虫剂中间体: 拟除虫菊酯类杀虫剂
- {SNA} Alcoholic & Nonalcoholic Beverages, Analytical Standards, Animal Products, Beef, Bread, Butter, Chicken, Cocoa, Coffee, Dairy Products, Flavor and Fragrance Standards, Food & Beverage Standards, Food and Cosmetic Component Standards, Fruits,
- {SNA} Alphabetical Listings,
- {SNA} Building Blocks, C4 to C7, Chemical Synthesis, Furans, Heterocyclic Building Blocks
产品应用
- 有机合成中间体,医药工业中用于制造维生素B1、磷酸氯喹和磷酸伯氨喹。
相关文献及参考
- Short: II/25D
- Buszewski, B., et al.: Biomed. Chromatogr., 21, 553 (2007),
- Ligor, T., et al.: J. Breath. Res., 1, 1 (2007),
- Short: II/14a
- McWilliams, et al.: Curr. Oncol. Rep., 4, 487 (2002),
- Has been used as a 5-carbon synthon in an enantioselective synthesis of pentitols by 5-lithiation followed by condensation with a chiral aldehyde. Subsequent opening of the furan ring was accomplished with bromine in acetonitrile: J. Am. Chem. Soc., 109, 3981 (1987).
- Beilstein:17(5)1,322
安全信息
GHS Symbol
- H330 Fatal if inhaled 吸入致命
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- H331 Toxic if inhaled 吸入中毒
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P305+P351+P338
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P304+P340+P310
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P337+P313
- P403+P233
- P303+P361+P353
- P284 Wear respiratory protection.? 佩戴呼吸保护装置。
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P370+P378
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P403+P235
- P304+P340+P312
- P241+P242+P243
- P305+P351+P338+P337+P313
- R11 Highly flammable 非常易燃
- R23 Toxic by inhalation 吸入有毒
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
- R36 Irritating to eyes 刺激眼睛
- R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S20 When using do not eat or drink 使用时,不得进食,饮水;
- S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
- S33 Take precautionary measures against static discharges 对静电采取预防措施;
- S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S4 Keep away from living quarters 远离生活区;
- S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
- S7/9 Keep container tightly closed and in a well-ventilated place 保持容器严格密闭,置于通风良好的场所;
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 455 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 46(2),68,1981
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 500 ppm/4H TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 50,A359,1989
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 730 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 46(2),68,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 46(2),68,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreporte
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 75300 umol/L REFERENCE : CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 13,89,1981
TYPE OF TEST : DNA repair TEST SYSTEM : Bacteria - Bacillus subtilis DOSE/DURATION : 160 ng/disc REFERENCE : DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 13,353,1986
其他信息
- 上游原料:氢 --> 重铬酸钠 --> 糠醛 --> 糠醇 --> 催化剂 --> 重铬酸钠 --> 硝酸铜 --> 加氢催化剂 --> 硝酸铜 --> 硝酸铜 --> 铜铝合金
- Alfa Aesar:2-甲基呋喃,98+%,stab.with150-400ppmBHT 2-Methylfuran, 98+%, stab. with 150-400ppm BHT(534-22-5)
- 外观性质:无色液体,有醚样气味,在空气中或阳光照射下变黄至黑色。
- 刺激数据:眼睛- 兔子 500毫克/24小时 轻度
- TCI Shanghai:2-甲基呋喃 2-Methylfuran,>;98.0%(GC)(534-22-5)
- 有醚样气味,在空气中或阳光照射下变黄至黑色,能与多种有机溶剂混溶,微溶于水(0.3g/100g)。在空气中变黄,能被强碱分解。有麻醉作用。
- 2-甲基呋喃价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M0226 2-甲基呋喃 2-Methylfuran 25ML 153元 2014/06/02 M0226 2-甲基呋喃 2-Methylfuran 500ML 480元 2010/06/21 126832500 2-甲基呋喃 2-Methylfuran 99%, stabilized 250 ML 1294元
- 海关编码:29321900
- 灭火剂:干粉、干砂、二氧化碳、泡沫、1211灭火剂
- 用途一:用于制取维生素B1、磷酸氯喹和磷酸伯氨喹等药物,合成菊酯类农药及香精香料,也是很好的溶剂
- 毒性分级:中毒
- 用途二:用作有机溶剂
- 类别:易燃液体
- FEMA:4179
- 图谱信息:2-甲基呋喃(534-22-5)核磁图( 13 CNMR) 2-甲基呋喃(534-22-5)红外图谱(IR2) 2-甲基呋喃(534-22-5)质谱(MS) 2-甲基呋喃(534-22-5)核磁图( 1 HNMR) 2-甲基呋喃(534-22-5)红外图谱(IR1)
- MSDS 信息:2-甲基呋喃(534-22-5).msds
- Acros Organics:2-甲基呋喃 2-Methylfuran, stabilized, 99%(534-22-5)
- 食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称 允许使用该种添加剂的食品中文名称 添加剂功能 最大允许使用量(g/kg) 最大允许残留量(g/kg) 2-甲基呋喃 食品 食品
- 急性毒性:口服- 大鼠
- 用途三:2-甲基呋喃是拟除虫菊酯烯丙菊酯、丙炔菊酯的中间体烯丙醇酮的原料,2-甲基呋喃又是良好的溶剂。
- 职业标准:STEL 1 毫克/ 立方米
- 可燃性危险特性:遇明火、高温、氧化剂易燃; 燃烧产生刺激烟雾
- 方法一:其制备方法是由糠醛用铜铝或铜为催化剂加氢制得。 加氢的最佳条件是压力300~500kPa,温度200~210
- 蒸气压:139 mm Hg ( 20 °
- 下游产品:4,5,6,7-四氢-2-甲基呋喃[2,3-C]并吡啶 --> 2-丙烯基-3-甲基-4-羟基-2-环戊烯-1-酮 --> 5-羟基-2-戊酮 --> 右旋烯丙菊酯 --> 5-甲基呋喃-2-硼酸 --> N,N-二甲基-5-甲基糠胺 --> 5-甲基-2-乙酰基呋喃 --> 2-甲基四氢呋喃 --> 2-乙基-6-甲基-3-羟基吡啶 --> 甲基环戊烯醇酮 --> 5-甲基呋喃醛 --> 2-甲基-3-呋喃硫醇
- 方法二:由糠醛(或糠醇)催化加氢制。加氢催化剂采用铜-铝合金,用碱作助催化剂,反应压力为0.3-0.5MPa,在200℃左右进行气相加氢,氢与糠醛摩尔比为10:1。反应产物经冷凝,蒸去水分,精馏而得成品。原料消耗定额:糠醛(96%)1400kg/t、氢气630m3kg/t、铜-铝催化剂114kg/t。