2-​Naphthoic Acid 2-萘甲酸

CAS 93-09-4 MFCD00004101

化学结构图

93-09-4
SMILES: O=C(O)c1ccc2ccccc2c1

化学属性

Mol. FormulaC11H8O2
Mol. Weight172
Melting Point185-187
Density1.08
Flash Point205°(401°F)
TSCAYes
Boiling Point300 ºC
Solubility<0.5 G/L (20 C)
Appearance 白色片状或针状结晶。熔点185.5℃,沸点300℃。溶于醚和醇,微溶于热水。

别名和识别编码

Chemical Name2-​Naphthoic Acid
Synonym 2-naphthalenecarboxylic acid 2-萘酸 B-NAPHTHOIC ACID 2-Carboxynaphthalene 2-Naphthalenecarboxylic acid ß-Naphthoic acid BETA-NAPHTHOIC ACID Naphthalene-beta-carboxylic acid
Beilstein Registry Number972039
PubChem Substance ID7123
CAS Number93-09-4
EC Number202-217-8
MDL NumberMFCD00004101
Reaxys-RN972039
Merck Number6382
Chemical Name Translation2-萘甲酸
Wiswesser Line NotationL66J CVQ
LabNetwork Molecule IDLN00225349
InChIInChI=1S/C11H8O2/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H,12,13)
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分类

  • Building Blocks, C11 to C12, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Organic Building Blocks
  • {uni_hamburg} no charge; carbocycle; aromatic; large ring; fused rings; 6ring; 10ring; carboxylic acid; 1fragment
  • {SNA} Building Blocks, C11 to C12, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Organic Building Blocks

相关文献及参考

  • Short: II/27B
  • The unprotected acid undergoes lithiation, e.g. with s-BuLi, by stereospecific 1,4-addition, providing a facile route to 1,2,2-trisubstituted 1,2-dihydronaphthalenes: J. Org. Chem., 61, 5206 (1996).

安全信息

Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P332+P313
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P302+P352+P332+P313+P362+P364
  • P302+P350
WGK Germany2
GHS Symbol
Signal word
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H303 May be harmfully swallowed 吞食可能有害
Hazard Codes Xi
RTECSQL1050000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,90,1982

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year: 4,379,1952

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,90,1982

其他信息

  • 海关编码:29163900
  • 图谱信息:2-萘甲酸(93-09-4)红外图谱(IR1) 2-萘甲酸(93-09-4)红外图谱(IR2) 2-萘甲酸(93-09-4)质谱(MS) 2-萘甲酸(93-09-4)核磁图( 13 CNMR) 2-萘甲酸(93-09-4)核磁图( 1 HNMR)
  • 用途一:用作植物生长调节剂
  • Alfa Aesar:2-萘甲酸,98+% 2-Naphthoic acid, 98+%(93-09-4)
  • MSDS 信息:2-Naphthalenecarboxylic acid(93-09-4).msds
  • Acros Organics:2-萘甲酸 2-Naphthoic acid, 99%(93-09-4)
  • 上游原料:1-萘甲腈
  • 下游产品:2-萘胺 --> 2-萘肼 --> 2-萘甲酰氯 --> 间萘二酚
  • 用途三:用作有机合成中间体及植物生长调节剂。
  • 检测方法:HPLC
  • TCI Shanghai:2-萘甲酸 2-Naphthoic Acid,>;98.0%(GC)(T)(93-09-4)
  • 方法一:由萘胺经亚硝酸钠重氮化、转换合成萘甲腈,再经水解、中和制得2-萘甲酸。
  • MOL 文件:93-09-4.mol
  • Sigma Aldrich:93-09-4(sigmaaldrich)
  • 用途二:用作植物生长刺激素,也用于有机合成
  • 2-萘甲酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 N0025 2-萘甲酸 2-Naphthoic Acid 25G 480元 2010/06/21 177321000 2-萘甲酸 2-Naphthoic acid 99% 100 GR 1093元 2010/06/21 177320250 2-萘甲酸 2-Naphthoic acid 99% 25 GR 977元

系列性分类


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