2-Hydroxycyclohepta-2,4,6-trienone 环庚三烯酚酮
CAS 533-75-5 MFCD00004158
化学结构图
SMILES: O=c1cccccc1O
化学属性
| Mol. Formula | C7H6O2 |
|---|---|
| Mol. Weight | 122 |
| Boiling Point | 80-84 |
| Melting Point | 50-54 |
| Density | 1.278 |
| Flash Point | >110°(230°F) |
| TSCA | No |
| Stability | 易吸潮 |
别名和识别编码
| Chemical Name | 2-Hydroxycyclohepta-2,4,6-trienone |
|---|---|
| Synonym | 2,4,6-Cycloheptatrien-1-one, 2-hydroxy- 2-HYDROXY-2,4,6-CYCLOHEPTATRIEN-1-ONE 2-Hydroxy-2,4,6-Cycloheptatrie 2-Hydroxy-2,4,6-cycloheptatrien-1-one 2-Hydroxy-2,4,6-cycloheptatrienone 2-Hydroxy-2,4,6-cycloheptatrienone; 2-Hydroxycyclohepta-2,4,6-trienone 2-Hydroxycyclohepta-2,4,6-trien-1-one 2-Hydroxycyclohepta-2,4,6-trienone 2-Hydroxytropone 2-hydroxycyclohepta-2,4,6-trienone 2-hydroxytropone 2-羟基-2,4,6-环庚三烯-1-酮 6-cycloheptatrien-1-one,2-hydroxy-4 Purpurocatechol TROPOLONE TROPOLONE 99+% Tropolone Tropolone,98% a-Tropolone {} {} {} {} {uni_ha α-Tropolone 【草(之上)+卓】酚酮 托酚酮 环庚三烯酚酮 环庚三烯酚酮/托酚酮 草酚酮,托酚酮 革酚酮 |
| MDL Number | MFCD00004158 |
| PubChem Substance ID | 10789 |
| Beilstein Registry Number | 1904978 |
| CAS Number | 533-75-5 |
| EC Number | 208-577-2 |
| Reaxys-RN | 1904978 |
| Chemical Name Translation | 环庚三烯酚酮 |
| Wiswesser Line Notation | L7VJ BQ |
| LabNetwork Molecule ID | LN00193176 |
| InChI | InChI=1S/C7H6O2/c8-6-4-2-1-3-5-7(6)9/h1-5H,(H,8,9) |
信息真实价格透明
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Building Blocks, C7 to C8, Carbonyl Compounds, Chemical Synthesis, Ketones, Organic Building Blocks
- {uni_hamburg} no charge; carbocycle; large ring; 7ring; ketone; alcohol; 1fragment
- {SNA} Building Blocks, C7 to C8, Carbonyl Compounds, Chemical Synthesis, Ketones, Organic Building Blocks
产品应用
- 医药中间体间。
相关文献及参考
- [2]. VardaKahn, et al.Inhibition of mushroom tyrosinase by tropolone Phytochemistry. Volume 24, Issue 5, 1985, Pages 905-908
- Beilstein: 8,IV,159
- Non-benzenoid aromatic system, analogous to phenol. For a review of 7-membered conjugated cyclic systems, see: Chem. Rev., 73, 293 (1973). For a study of the role of chelation and resonance in the intrinsic acidity and basicity of tropolone, see: J. Org. Chem., 62, 3200 (1997).
- Reagent for Rh: Mikrochim. Acta, 459 (1972).
- Short: II/2
- Short: II/24B
- [1]. Donald D Nolting,et al. Synthesis of bicyclo[5.3.0]azulene derivatives. Nat Protoc. 2009; 4(8): 1113–1117.
- [1]. Donald D Nolting,et al. Synthesis of bicyclo[5.3.0]azulene derivatives. Nat Protoc. 2009; 4(8): 1113–1117.
- [2]. VardaKahn, et al.Inhibition of mushroom tyrosinase by tropolone Phytochemistry. Volume 24, Issue 5, 1985, Pages 905-908
安全信息
GHS Symbol
- S22 Do not breathe dust 不要吸入粉尘；
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 106 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 92,19,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 190 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Behavioral - rigidity (including catalepsy) REFERENCE : TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 14,217,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 233 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - analgesia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 91,550,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 212 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Behavioral - rigidity (including catalepsy) REFERENCE : TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1
其他信息
- 海关编码:29144090
- 用途二:医药中间体间。
- 环庚三烯酚酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 T0606 环庚三烯酚酮 Tropolone 1G 220元 2014/06/02 T0606 环庚三烯酚酮 Tropolone 25G 1900元 2014/06/02 T0606 环庚三烯酚酮 Tropolone 5G 750元
- Alfa Aesar:品托酮,98% Tropolone, 98%(533-75-5)
- 外观性质:浅黄色结晶。沸点：80-84 °C/0.1 mmHg熔点：50-52 °C闪点：112 °C
- Acros Organics:环庚三烯酚酮/托酚酮 Tropolone, 98%(533-75-5)
- Sigma Aldrich:533-75-5(sigmaaldrich)
- MOL 文件:533-75-5.mol
- 敏感性:Hygroscopic
- F:8-10-23
- TCI Shanghai:环庚三烯酚酮 Tropolone,>;98.0%(GC)(T)(533-75-5)
- 图谱信息:环庚三烯酚酮(533-75-5)红外图谱(IR1)
- 七碳环状化合物:环庚三烯酚酮是一种七碳环状化合物，又称托酚酮、2-羟庚芳酮，呈弱酸性，具有芳香族化合物的特性，双键性和弱酮基性。在自然界中已知含有七碳环状的化合物有以下十余种： 1，日桧醇（hinokitiol）作为红色铁络合物存在于台湾丝柏木材中。 2，α-和γ-守侧素（thujapricin，β-体与日桧醇相同）存在于丝柏和针叶类植物中。它作为金钟柏属植物的抗菌物质对木材具有防腐作用。 3，α-及β-体在丝柏精油中也有存在。密挤青霉酸（stipitatic acid，6-羟基芳庚酮-4-羧酸）作为青霉菌属的代谢产物而形成，具有抗菌作用。 4，红紫棓精（purpurogallin）作为糖苷存在于壳斗科檞属植物虫瘿里，可被用作酚氧化酶试验。 5，努特卡扁柏（Cha- maecyparis nootkatensis）心材中的努特卡扁柏素（nootkatin）和作为抑制物质的秋水仙素及其类似的秋水仙属（Colchicum）的副生物碱类。 根据如上化合物的性质，科学家推测托酚酮会在活体成分代谢过程中起着重要作用。在1936年首先由日本科学家野副铁男在研究日桧醇时候开始关注环庚三烯酚酮，而欧美是在研究密挤青霉酸（stipitatic acid）和秋水仙素的结构开始，更深入的研究是在1950年以后了。
- 用途一:用作医药、染料中间体
- MSDS 信息:2-Hydroxycyclohepta-2,4,6-trienone(533-75-5).msds
