2-Chloropropionic Acid 2-氯丙酸
CAS 598-78-7 MFCD00004224
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} Building Blocks, C1 to C5, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Organic Building Blocks
- {uni_hamburg} no charge; carboxylic acid; racemate; 1fragment
- {Chemicalbook} 农药中间体: 杀菌剂中间体: 酰胺类杀菌剂
产品应用
- 用于有机合成及作为除草剂的中间体。
相关文献及参考
- Condensation of the dilithio-derivative with carbonyl compounds gives ɑß-epoxycarboxylic acids (glycidic acids) which afford methyl ketones on decarboxylation, avoiding possible ester hydrolysis in the classical Darzens glycidic ester condensation (see Ethyl chloroacetate, A15554): J. Org. Chem., 47, 1205 (1982). An analogous reaction of the dianion with ɑß-unsaturated esters gives, stereoselectively, cyclopropane cis-dicarboxylic acids: Synthesis, 284 (1982):
- Beilstein:2,248
- Short: EINECS
- Short: III/35E
- Short: III/38B
安全信息
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R35 Causes severe burns 会导致严重灼伤
- R22 Harmful if swallowed 吞咽有害
- R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
- S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
- S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
GHS Symbol
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H302 Harmful if swallowed 吞食有害
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P303+P361+P353+P310+P363
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P405 Store locked up. 上锁保管。
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
- P308+P311
- P303+P361+P353
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P304+P340+P310
- P304+P340+P311
- P403+P233
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P305+P351+P338+P310
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Kidney, Ureter, Bladder - hematuria Skin and Appendages - hair REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555355
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 126 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 5,136(89),1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Kidney, Ureter, Bladder - hematuria Skin and Appendages - hair REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555355
其他信息
- 职业标准:TLV-TWA 0.1 PPM; STEL 2 毫克/ 立方米
- 用途四:主要用于生产农药除草剂。2-氯丙酸还用于生产乳酸及有工业价值的低级醇酯。。
- 蒸气压:4 mm Hg ( 20 °C)
- 急性毒性:皮下- 豚鼠 LD50: 126 毫克/ 公斤
- MSDS 信息:2-氯丙酸(598-78-7).msds
- 可燃性危险特性:可燃;加热分解有毒氯化物烟雾
- 储运特性:库房通风低温干燥; 与氧化剂、碱类分开存放。
- MOL 文件:598-78-7.mol
- 外观性质:无色液体,有特殊臭味。
- Acros Organics:2-氯丙酸 2-Chloropropionic acid, 95%(598-78-7)
- 海关编码:29159080
- 类别:腐蚀物品
- 方法二:由丙酸氯化而得。
- 用途三:α-氯代丙酸是杀菌剂甲霜灵、苯霜灵、恶霜灵,除草剂禾草灵、喹禾灵、吡氟禾草灵、噻唑禾草灵、恶唑禾草灵、氟吡禾灵、乳氟禾草灵和茅草枯、2,4滴丙酸盐、2甲4氯丙酸盐等的中间体。
- 方法一:其制备方法是在反应釜内加入丙酸和一定量的催化剂PCl 3 ,在120~125℃下通入氯气,控制反应物的相对密度,达到反应终点,停止通氯气,降温至室温,用空气或氮气赶走多余的氯气和氯化氢,经减压分馏得到产品。 CH 3 CH 2 COOH+Cl 2 [PCl 3 ]→CH 3 CHClCOOH+HCl
- 图谱信息:2-氯丙酸(598-78-7)红外图谱(IR1) 2-氯丙酸(598-78-7)质谱(MS) 2-氯丙酸(598-78-7)核磁图( 1 HNMR) 2-氯丙酸(598-78-7)Raman光谱 2-氯丙酸(598-78-7)核磁图( 13 CNMR)
- 2-氯丙酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 L0731802 (+/-)-2-氯丙酸98% 500g 504元 2011/04/16 C0275 2-氯丙酸 2-Chloropropionic Acid 500G 560元 2011/04/16 C0275 2-氯丙酸 2-Chloropropionic Acid 25G 131元
- 上游原料:氯 --> 丙酸
- 灭火剂:砂土、泡沫、雾状水、二氧化碳
- 用途一:用于有机合成
- 用途五:用于有机合成及作为除草剂的中间体。
- 有特殊臭味,与水混溶,可混溶于乙醚、苯、丙酮、四氯化碳等大多数有机溶剂。
- 毒性分级:高毒
- Alfa Aesar:(±)-2-氯丙酸,97% (+/-)-2-Chloropropionic acid, 97%(598-78-7)
- 用途二:用于农药、医药、染料中间体及其他有机合成
- 下游产品:L-丙氨酸 --> DL-丙氨酸 --> 萘丙胺 --> 布洛芬 --> 敌草胺 --> 2,4-滴丙酸 --> N,N-二乙基-2-氯丙酰胺
- Sigma Aldrich:598-78-7(sigmaaldrich)
- TCI Shanghai:2-氯丙酸 2-Chloropropionic Acid,>;98.0%(GC)(T)(598-78-7)