Propiolic Acidd 丙炔酸粗品
CAS 471-25-0 MFCD00004360
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Building Blocks, C1 to C5, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Organic Building Blocks
- {uni_hamburg} no charge; carboxylic acid; 1fragment
产品应用
- 用于有机合成。
相关文献及参考
- Short: II/19b
- Short: II/14a
- Merck: 14,7821 Beilstein:2,477
- Merck: 14,7821
- Alkylation of the dilithio-derivative leads to higher 2-alkynoic acids. Reaction with epoxides, partial reduction (Lindlar) of the triple bond and cyclization has been used in the synthesis of unsaturated lactones: Tetrahedron Lett., 2615 (1974); J. Org. Chem., 40, 1610 (1975).
- Short: II/22a
安全信息
GHS Symbol
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P233 Keep container tightly closed. ?保持容器密闭。
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
- P241+P242+P243
- P242 Use only non-sparking tools. 只能使用无火花工具。
- P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310
- P301+P330+P331
- P301+P330+P331+P310
- P302+P350
- P302+P352
- P303+P361+P353
- P303+P361+P353+P310+P363
- P304+P340
- P304+P340+P310
- P305+P351+P338
- P305+P351+P338+P310
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
- P330 Rinse mouth. 漱口
- P332+P313
- P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
- P370+P378
- P403+P233
- P403+P235
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H226 Flammable liquid and vapour 易燃液体和蒸气
- H301 Toxic if swallowed 吞食有毒
- H310 Fatal in contact with skin 皮肤接触致命
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 25 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4953,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4953,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4953,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 38MKAJ "Patty
其他信息
- 海关编码:29161980
- 具有炔烃和羧酸的双重特性,能进行还原、加成、氧化、酯化和环化以及生成盐和酰氯等反应。溶于水。
- 丙炔酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P0497 丙炔酸 Propiolic Acid 5G 214元 2014/06/02 P0497 丙炔酸 Propiolic Acid 25G 604元 2010/06/21 131500100 丙炔酸 Propiolic acid 98% 10 ML 662元
- 灭火剂:水、二氧化碳、砂土
- MSDS 信息:丙炔酸(471-25-0).msds
- TCI Shanghai:丙炔酸 Propiolic Acid,>;97.0%(GC)(T)(471-25-0)
- Acros Organics:2-丙炔酸 Propiolic acid, 98%(471-25-0)
- 外观性质:无色粘稠液体。
- 用途二:用于有机合成。可用于制取丙酸、均苯三甲酸、卤代丙烯酸、二卤代丙烯酸、二乙炔二羧酸、丙炔酸乙酯、吡唑啉酮、二溴巴豆酸,乙氧基巴豆酸等。丙炔酸与硫酸、甲醇加热回流可制得丙炔酸甲酯(C4H4O2,[922-67-8]),是抗病毒药物碘苷的原料。
- F:3-8
- 下游产品:3-氨基异恶唑 --> 3Β,17Β-二羟基孕甾-5-烯-21-羧酸-Γ-内酯 --> 3Β,17Β-二羟基孕甾-5-烯-21-羧酸
- 急性毒性:口服-大鼠 LC50: 100 毫克/公斤; 口服-小鼠 LD50: 100 毫克/公斤
- 类别:腐蚀物品
- Alfa Aesar:丙炔酸,98+% Propiolic acid, 98+%(471-25-0)
- 方法一:1.由丙炔醇氧化而得。将丙炔醇加入丙酮中搅拌,于20℃滴加铬酐的硫酸溶液,加毕,室温搅拌14h,即生成丙炔酸。2.以乙炔钠和CO2在3.55-7.09MPa和90℃以下温度反应,即得。
- MOL 文件:471-25-0.mol
- 图谱信息:丙炔酸(471-25-0)红外图谱(IR1) 丙炔酸(471-25-0)质谱(MS)
- 可燃性危险特性:遇热可燃
- 上游原料:发烟硫酸 --> 三氧化铬 --> 2-丙炔-1-醇 --> 乙炔钠
- 毒性分级:高毒
- Sigma Aldrich:471-25-0(sigmaaldrich)
- 用途一:用作有机合成中间体,可与甲醇在硫酸催化下生成丙炔酸甲酯,是生产抗病毒药物碘苷的原料
- 储运特性:库房通风低温干燥; 与氧化剂、碱分开存放