Diphenylmethanol 二苯甲醇
CAS 91-01-0 MFCD00004488
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资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} Alcohols, Building Blocks, C11 to C30+, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds
- {SA} Alcohols, Building Blocks, C11 to C30+, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds
- Pharmaceuticals
- Intermediates & Fine Chemicals
- {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; alcohol; 1fragment
- Aromatics
- {SNA} Analytical Standards, EP Standards, EP Standards C - D, Pharmacopeia Metrological Institutes Standards, 分析/色谱
- {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, EP Standards, EP Standards C - D, Pharmaceutical Standards, Pharmacopeia Standards
产品应用
- 主要用于有机合成,医药工业作为苯甲托品,苯海拉明的中间体。
相关文献及参考
- Short: III/35D2
- Short: II/27B
- Merck: 14,1090 Beilstein:6,678
- The protection of OH groups as benzhydryl ethers can be catalyzed by sulfuric acid: Org. Synth. Coll., 4, 72 (1963); Angew. Chem. Int. Ed., 15, 281 (1976). See also Benzhydryl bromide, L02211. Thiols, e.g. in cysteine residues in peptide synthesis, can be protected as thioethers in the presence of TFA or HBr/AcOH: J. Chem. Soc. (C), 2683 (1970). The group can be cleaved by TFA in the presence of a cation scavenger, e.g. phenol or anisole (same ref.), or by Na in liquid NH3: J. Am. Chem. Soc., 84, 3887 (1962). See Appendix 6.
- Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),
- Carboxyl groups can be protected by esterification in benzene with tosic acid catalyst. Deprotection can be effected with the same catalyst by refluxing in toluene, which undergoes electrophilic alkylation: Tetrahedron Lett., 37, 1965 (1996).
- Merck: 14,1090
安全信息
GHS Symbol
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P332+P313
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- P305+P351+P338+P337+P313
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H303 May be harmfully swallowed 吞食可能有害
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 24,405,1925
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,713,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,713,1979
其他信息
- TCI Shanghai:二苯甲醇 Benzhydrol,>;99.0%(GC)(91-01-0)
- 二苯甲醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 AB485602 二苯基甲醇 100g 433元 2011/08/23 30075481 二苯基甲醇 100g 400元 2011/04/16 D0898 二苯甲醇 Benzhydrol 500G 869元
- Alfa Aesar:二苯基甲醇,99% Benzhydrol, 99%(91-01-0)
- 易溶于乙醇、醚、氯仿和二硫化碳。水中溶解度:0.5 g/L (20°C)
- 用途二:主要用于有机合成,医药工业作为苯甲托品,苯海拉明的中间体。
- 图谱信息:二苯甲醇(91-01-0)红外图谱(IR1) 二苯甲醇(91-01-0)质谱(MS) 二苯甲醇(91-01-0)红外图谱(IR2) 二苯甲醇(91-01-0)Raman光谱 二苯甲醇(91-01-0)核磁图( 13 CNMR) 二苯甲醇(91-01-0)核磁图( 1 HNMR)
- MSDS 信息:Diphenylcarbinol(91-01-0).msds
- MOL 文件:91-01-0.mol
- Hazard Note:Irritant
- 海关编码:29062900
- 用途一:用作医药中间体,用于合成苯甲托品、苯海拉明等药物
- Acros Organics:二苯基甲醇 Benzhydrol, 99%(91-01-0)
- Sigma Aldrich:91-01-0(sigmaaldrich)
- 上游原料:锌粉 --> 二苯甲酮
- 下游产品:酸性蓝 74 --> 奈福泮 --> 二苯甲基哌嗪 --> 氯代(邻氯苯基)二苯基甲烷 --> (2-氯苯基)二苯基甲醇 --> C.I.酸性绿16