D-Bicuculline 右旋比扣扣灵碱
CAS 485-49-4 MFCD00005006
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资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
一流品牌服务
分类
- {SNA} B, Bioactive Small Molecules, Cell Biology
- Pharmaceuticals
- {SNA} B, Bioactive Small Molecules, 细胞生物学
- {SNA} B, Bioactive Small Molecule Alphabetical Index, 生物活性小分子, 细胞生物学
- Intermediates & Fine Chemicals,
- {uni_hamburg} no charge; oxygen heterocycle; nitrogen heterocycle; carbocycle; aromatic; alicycle; large ring; fused rings; 5ring; 6ring; 9ring; 10ring; 12ring; 13ring; ester; lactone; chiral; 1fragment
产品应用
- GABAA受体竞争性拮抗剂,是研究GABA能突触传递的重要工具。
相关文献及参考
- Chebib, M., et al.: Clin. Exp. Pharmacol. Physiol., 26, 927 (1999),
- Short: III/10b
- Short: EINECS
- Curtis, et al.: Nature, 226, 1222 (1970),
- Avoli, M., et al.: J. Physiol. Pharmacol., 75, 526 (1997),
- Merck: 14,1203 Beilstein: 27,IV,6900
- Merck: 14,1203
安全信息
GHS Symbol
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
- R50 Very toxic to aquatic organisms 对水生生物极毒
- H301+H311+H331
- H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
- H311+H331
- H300 Fatal if swallowed 吞食致命
- H331 Toxic if inhaled 吸入中毒
- H311 Toxic in contact with skin 皮肤接触中毒
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310+P330
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P273 Avoid release to the environment. 避免释放到环境中。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P405 Store locked up. 上锁保管。
- P304+P340+P311
- P302+P352+
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P302+P350
- P403+P233
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 8480 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CUTOEX Current Toxicology. (Nova Science Publishers, Inc., 6080 Jericho Turnpike, Suite 207, Commack, NY 11725) V.1 1993- Volume(issue)/page/year: 1,199,1993
其他信息
- 储运特性:通风低温干燥; 与库房食品原料分开存放
- 毒性分级:剧毒
- 可燃性危险特性:可燃; 燃烧产生有毒氮氧化物烟舞
- 类别:农药
- MOL 文件:485-49-4.mol
- 溶于苯、氯仿、乙酸乙酯。微溶于乙醇和乙醚。
- 存储注意事项:空气敏感;光敏感
- F:10-23
- MSDS 信息:(R-(R*,S*))-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-furo(3,4-e)-1,3-benzodioxol-8(6H)-one(485-49-4).msds
- Sigma Aldrich:485-49-4(sigmaaldrich)
- 急性毒性:腹腔-小鼠 LD50: 8.48 毫克/公斤
- 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
- 图谱信息:(+)-荷包牡丹碱(485-49-4)核磁图( 1 HNMR) (+)-荷包牡丹碱(485-49-4)红外图谱(IR1) (+)-荷包牡丹碱(485-49-4)核磁图( 13 CNMR) (+)-荷包牡丹碱(485-49-4)红外图谱(IR2) (+)-荷包牡丹碱(485-49-4)质谱(MS)