2-METHYLAZIRIDINE 2-甲基氮丙啶
CAS 75-55-8 MFCD00005118
化学结构图
SMILES: CC1CN1
化学属性
| Mol. Formula | C3HD6N |
|---|---|
| Mol. Weight | 63 |
| Refractive index | n20/D 1.4125(lit.) |
| Boiling Point | 66-67 °C(lit.) |
| Density | 0.808 g/mL at 25 °C(lit.) |
| Vapor Pressure | 140 mmHg ( 25 °C) |
| Flash Point | -4 ºC |
| Melting Point | -65 ºC |
| Solubility | MISCIBLE |
别名和识别编码
| Chemical Name | 2-METHYLAZIRIDINE |
|---|---|
| CAS Number | 75-55-8 |
| Synonym | rcrawastenumberp067 1,2-Propylenimine Methylaziridine RCRA waste number P067 丙烯亚胺 2-methylaziridine PI propilenimina Propenimin ai3-50325 1,2-propylenimine(2-methylaziridine) propyleneimine,inhibited 2-Methylethylenimine 1,2-Propyleneimine Rcra waste number P067 2-Propylene Imine (PI) Aziridine, 2-methyl- Propyleneimine 2-methyl-aziridin (R,S)-2-Methyl-aziridine 2-Methylaziridine cis-2-Methylaziridine 丙撑亚胺 propyleneimine DL-2-Methylaziridine Propylenimine Propyleneimine, inhibited Propylene imine 2-甲基氮丙啶 Methylethylenimine PROPYLENEIMINE 2-METHYLAZIRIDINE 2-Methylazacyclopropane |
| PubChem Substance ID | 6377 |
| EC Number | 200-878-7 |
| Beilstein Registry Number | 0102386 |
| MDL Number | MFCD00005118 |
| Chemical Name Translation | 2-甲基氮丙啶 |
| Wiswesser Line Notation | T3MTJ B1 |
| InChI | InChI=1S/C3H7N/c1-3-2-4-3/h3-4H,2H2,1H3 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Aziridines, Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks
- {uni_hamburg} no charge; nitrogen heterocycle; alicycle; 3ring; 1fragment
- {SNA} Aziridines, Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks
产品应用
- The renal papillary toxin.
相关文献及参考
- Guengerich, F., et al.: Drug Metab. Dispos., 25, 1234 (1997),
- Mekenyan, O., et al.: Toxicol. Sci., 58, 270 (2000),
- Westwood, I., et al.: Biochem. J., 385, 605 (2005),
- Beil. 20 ,V,1,150
- Corp MSDS 1 (2), 2295:C / FT-NMR 1 (1), 557:A / RegBook 1 (1), 377:A / Sax 6 , 1805 / Structure Index 1 , 53:D:3 / Vapor Phase 3 , 441:B
- Short: II/14a Title: Molecular Constants: Diamagnetic Molecules Author: Demaison, J.; Dubrulle, A.; Hüttner, W.; Tiemann, E. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/14a Page: 1-788 Year: 1982 Keyword: organic compounds; molecular constants; spectroscopy; microwave spectroscopy ISBN: 3-540-11365-7 ISBN: 978-3-540-11365-2 Internet Resource: DOI:10.1007/b19966 RefComment: 196 figs., XI
- Short: II/2 Title: Magnetic Properties of Coordination and Organometallic Transition Metal Compounds Author: König, E. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/2 Year: 1966 ISBN: 3-540-03593-1 ISBN: 978-3-540-03593-0 Internet Resource: DOI:10.1007/b19948 RefComment: 170 figs., XII, 578 pages. Hardcover Abstract: The data compiled refer to susceptibility measurements (susceptibility, Curie-constants, magnetic moments, transition temperatures) and ESR-measurements (g-factors and other parameters of the applied spin Hamiltonian). In volume II/2 the literature from 1899 up to 1964 has been considered. Volume II/8 supplements volume II/2, taking into account the data on magnetic susceptibilities and ESR parameters published in the p eriod 1964 to 1968. The following subvolumes II/10,II/11, II/12 supplement data up to 1974.
- Short: II/25C Title: Structure Data Of Free Polyatomic Molecules: Molecules containing Three or Four Carbon Atoms Author: Graner, G.; Hirota, E.; Iijima, T.; Kuchitsu, K.; Ramsay, D.A.; Vogt, J.; Vogt, N. Editor: Kuchitsu, K. Source: Landol
安全信息
GHS Symbol
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H330 Fatal if inhaled 吸入致命
- H310 Fatal in contact with skin 皮肤接触致命
- H300 Fatal if swallowed 吞食致命
- H350 May cause cancer 可能致癌
- H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- R11 Highly flammable 非常易燃
- R51/53
- R45 May cause cancer 可能致癌
- R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
- R35 Causes severe burns 会导致严重灼伤
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4129 mg/kg/58W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 67,75,1981
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1120 mg/kg/28W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Brain and Coverings - tumors Skin and Appendages - tumors REFERENCE : NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 230,460,1971
TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3920 mg/kg/27W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Blood - leukemia Skin and Appendages - tumors REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 67,75,1981
TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 500 ppm/4H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,343,1949
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 43 mL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 355 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 62,911,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 19 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLA
TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES O
TYPE OF TEST : Micronucleus test ROUTE OF EXPOSURE : Intraperitoneal TEST SYSTEM : Rodent - mouse DOSE/DURATION : 10 mg/kg REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 389,3,1997
TYPE OF TEST : Morphological transformation TEST SYSTEM : Rodent - hamster Embryo DOSE/DURATION : 1 mg/L REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 67,1303,1981
TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 300 umol/L/1H REFERENCE : BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 72,732,1976
TYPE OF TEST : Morphological transformation TEST SYSTEM : Rodent - mouse Fibroblast DOSE/DURATION : 80 ug/L REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 67,1303,1981
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 10 ug/plate REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 6(Suppl 2),1,1984
TYPE OF TEST : DNA repair TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 2 ug/plate REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information,
其他信息
- 储运特性:库房通风低温干燥; 与酸, 氧化剂分开储运存放
- 职业标准:TLV-TWA 5 毫克/立方米
- MOL 文件:75-55-8.mol
- Sigma Aldrich:75-55-8(sigmaaldrich)
- 外观性质:无色易燃液体, 呈碱性, 具氨样气味。
- 灭火剂:干粉, 二氧化碳; 1211; 泡沫
- 可燃性危险特性:易燃; 受热分解有毒胺蒸气
- 类别:易燃液体
- 刺激数据:眼睛-兔子 250 微克 重度
- 爆炸物危险特性:与空气混合可爆
- MSDS 信息:丙撑亚胺(75-55-8).msds
- 毒性分级:剧毒
- 急性毒性:口服-大鼠 LD50: 19 毫克/公斤; 吸入-大鼠 LCL0:1.25 克/立方米/4小时
