CAS 36011-19-5 MFCD00005178-细胞松驰素 E 细胞松驰素 E TAO{mole}

细胞松驰素 E 细胞松驰素 E

CAS 36011-19-5 MFCD00005178

化学结构图

SMILES: C[C@]12O[C@H]1[C@@H]1C=CC[C@H](C)C(=O)[C@](C)(O)C=COC(=O)O[C@]31[C@H]([C@H](CC1C=CC=CC=1)NC3=O)[C@@H]2C |c:28,30,t:6,16,32|

化学属性

Mol. Formula	C28H33NO7
Mol. Weight	496
Melting Point	225

别名和识别编码

Chemical Name	Cytochalasin E from Aspergillus clavatus
MDL Number	MFCD00005178
PubChem Substance ID	24892467
Beilstein Registry Number	1096975
EC Number	252-835-7
Synonym	Cytochalasin E from Aspergillus clavatus 松胞菌素 E 来源于棒曲霉
Chemical Name Translation	细胞松驰素 E
CAS Number	36011-19-5

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品牌质保精细包装现货库存一流品牌服务

安全信息

WGK Germany3

GHS Symbol

Precautionary statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P301+P310
P302+P350

Hazard statements

H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
H330 Fatal if inhaled 吸入致命
H310 Fatal in contact with skin 皮肤接触致命
H300 Fatal if swallowed 吞食致命

RTECSHA5360000

Signal word Danger

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Hazard Codes 6.1 T+

Safety Statements

S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

Risk Statements

R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
R63 Possible risk of harm to the unborn child 可能危害未出生婴儿

UN Number 1544

Packing GroupII

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 9100 ug/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - coma
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   32,135,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 500 ug/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - coma
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   32,135,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2600 ug/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - coma
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   32,135,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intratracheal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1300 ug/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - coma
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   32,135,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent k

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3900 ug/kg
SEX/DURATION            : female 7-9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 25,11,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3600 ug/kg
SEX/DURATION            : female 7-9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 25,11,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 8100 ug/kg
SEX/DURATION            : female 7-9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 38,438,1979