CAS 305-84-0 MFCD00005207-L-Carnosine, 98%, reference material L-肌肽 TAO{mole}

L-Carnosine, 98%, reference material L-肌肽

CAS 305-84-0 MFCD00005207

化学结构图

SMILES: NCCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

化学属性

Mol. Formula	C9H14N4O3
Mol. Weight	226.23
Melting Point	253°C
Appearance	crystalline 白色粉末。
Refractive index	21 ° (C=2, H2O)
Density	1.375
Solubility	Soluble in 80% acetic acid (10 mg/ml), and water (1:3.1).
Stability	易吸潮
Boiling Point	656.2°C at 760 mmHg
Flash Point	350.7°C

别名和识别编码

Chemical Name	L-Carnosine, 98%, reference material
MDL Number	MFCD00005207
CAS Number	305-84-0
Synonym	L-Carnosine {LY} L-Carnosine {} {LY} L-Carnosine {} {} {LY} L-Carnosine {} {} {} {LY} L-Carnosine {} {} {} {} {LY} L-Carnosine {} {} {} {} {} {LY} L-Carnosine {} {} {} {} {} {} {LY} L-Carnosine {} {} {} {} {} {} {} {LY} L-Carnosine {} {} {} {} {} {} {} {} {LY} L-Carnosine {} {} {} {} {} {} {} {} {} {LY} L-Carnosine {} {} {} {} {} {} {} {} {} {} {} β-Alanyl-L-histidine
PubChem Substance ID	439224
Beilstein Registry Number	87671
EC Number	206-169-9
Reaxys-RN	87671
Merck Number	1850
Chemical Name Translation	L-肌肽
Wiswesser Line Notation	T5M CNJ D1YVQMV2Z
LabNetwork Molecule ID	LN00196768
InChI	InChI=1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1
Canonical SMILES	OC([C@@H](NC(CCN)=O)CC1=CN=CN1)=O

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产品应用

二肽，具潜在的抗氧剂和抗糖基化活性；阻止乙醛诱导的非酶糖基化和蛋白质偶联。也是肌肽酶检测的底物。具细胞抗氧化，维持机体pH平衡，延长细胞寿命。

安全信息

WGK Germany2

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

RTECSMS3080000

Storage condition polypeptide, sealed storage, away from moisture and light {LY} polypeptide, sealed storage, away from moisture and light {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {} {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {} {} {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {} {} {} {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {} {} {} {} {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {LY} polypeptide, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {LY} polypeptide, sealed storage

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >14930 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4446149

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9087 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4446149

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 21 mg/kg
SEX/DURATION            : female 8-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 8,1219,1974

Precautionary statements

P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。

Hazard statements

其他信息

用途一:细胞抗氧化，维持机体pH平衡，延长细胞寿命。
Acros Organics:L-肌肽 L-Carnosine, 98%(305-84-0)
类别:有毒物质
灭火剂:水,二氧化碳, 泡沫, 干粉
比旋光度:20.9 ° (c=1.5, H2O)
储运特性:库房低温通风干燥
可燃性危险特性:热分解排出有毒氮氧化物烟雾
毒性分级:低毒
F:3-10
L-肌肽是一种二肽，以毫摩尔浓度出现在大脑、肌肉和眼睛的晶状体上。
MSDS 信息:L-Carnosine(305-84-0).msds
TCI Shanghai:β-丙氨酰基-L-组氨酸 beta-Alanyl-L-histidine,>;98.0%(LC)(T)(305-84-0)
MOL 文件:305-84-0.mol
用途二:二肽，具潜在的抗氧剂和抗糖基化活性；阻止乙醛诱导的非酶糖基化和蛋白质偶联。也是肌肽酶检测的底物。具细胞抗氧化，维持机体pH平衡，延长细胞寿命。
急性毒性:口服-小鼠 LD50: >; 14930 毫克/公斤; 腹腔-小鼠 LD50: 9087 毫克/公斤
Sigma Aldrich:305-84-0(sigmaaldrich)
图谱信息:L-肌肽(305-84-0)红外图谱(IR1) L-肌肽(305-84-0)质谱(MS) L-肌肽(305-84-0)红外图谱(IR2)
L-肌肽价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 xp620105 L-肌肽;L-肉缩氨基酸; β-丙氨酰-L-组氨酸 1g 42元 2011/04/16 A0222 β-丙氨酰基-L-组氨酸 beta-Alanyl-L-histidine 1G 284元 2011/04/16 A0222 β-丙氨酰基-L-组氨酸 beta-Alanyl-L-histidine 5G 971元