CAS 108-50-9 MFCD00006148-2,6-Dimethylpyrazine 2,6-二甲基吡嗪 TAO{mole}

2,6-Dimethylpyrazine 2,6-二甲基吡嗪

CAS 108-50-9 MFCD00006148

化学结构图

SMILES: CC1C=NC=C(C)N=1

化学属性

Mol. Formula	C6H8N2
Mol. Weight	108.144
Density	0.965
Boiling Point	154°C at 760 mmHg
Melting Point	32-40°C
Refractive index	1.5000
Flash Point	52°C(lit.)
TSCA	Yes
Appearance	白色至黄色块状结晶，具有咖啡和炒花生的气味。熔点48℃，沸点155℃。溶于水和有机溶剂。

别名和识别编码

Chemical Name	2,6-Dimethylpyrazine
CAS Number	108-50-9
Alfabeta Name	DIMETHYLPYRAZINE 26-,
MDL Number	MFCD00006148
EC Number	203-589-4
Beilstein Registry Number	23,97
Synonym	2,6-Dimethylpyrazine {LY} 2,6-Dimethylpyrazine {} {LY} 2,6-Dimethylpyrazine {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dimethylpyrazine {} {} {} {} {} {
PubChem Substance ID	87568014
Reaxys-RN	1726
Chemical Name Translation	2,6-二甲基吡嗪
Wiswesser Line Notation	T6N DNJ B1 F1
LabNetwork Molecule ID	LN00176881
Canonical SMILES	CC1=CN=CC(C)=N1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

Warnings IRRITANT

Signal word Danger

GHS Symbol

WGK Germany3

Safety Statements

S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S39 Wear eye/face protection 戴眼睛/面孔保护装置；

Risk Statements

R10 Flammable 易燃
R11 Highly flammable 非常易燃
R22 Harmful if swallowed 吞咽有害
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
R41 Risk of serious damage to eyes 有严重损伤眼睛的危险

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P312+P330
P302+P352+P332+P313+P362+P364
P305+P351+P338
P305+P351+P338+P337+P313
P332+P313
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H228 Flammable solid 易燃固体
H315 Causes skin irritation 会刺激皮肤
H318 Causes serious eye damage 严重伤害眼睛
H302 Harmful if swallowed 吞食有害
H335 May cause respiratory irritation 可能导致呼吸道刺激

Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

RTECSUQ2975000

Packing GroupII

UN Number 1325 UN1325

Hazard Codes 4.1 F,Xn Xn

Hazard Class4.1

Storage condition 2-8°C {LY} 2-8°C Flammables area {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 880 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 3,249,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1080 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   17,244,1970

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 3300 mg/L
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 18,581,1980

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 2500 mg/L
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 18,581,1980

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 4 umol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 321,213,1994

其他信息

用途一:用于各种食品、加工品、香精
图谱信息:2,6-二甲基吡嗪(108-50-9)核磁图( 13 CNMR) 2,6-二甲基吡嗪(108-50-9)核磁图( 1 HNMR) 2,6-二甲基吡嗪(108-50-9)质谱(MS)
下游产品:2,6-二甲基哌嗪 --> 2-乙基-3,5-二甲基吡嗪
MSDS 信息:2,6-Dimethyl-1,4-diazine(108-50-9).msds
2,6-二甲基吡嗪价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 D1527 2,6-二甲基吡嗪 2,6-Dimethylpyrazine 25G 730元 2014/06/02 D1527 2,6-二甲基吡嗪 2,6-Dimethylpyrazine 5G 231元 2010/06/21 116690050 2,6-二甲基吡嗪 2,6-Dimethylpyrazine 96%, balance 2,5-isomer 5 GR 542元
Sigma Aldrich:108-50-9(sigmaaldrich)
含量分析:按气相色谱法(GT-10-4)中的极性柱方法测定。
上游原料:1,2-丙二胺 --> 2,5-二甲基吡嗪
用途二:GB 2760—2001规定为允许使用的食品用香料。主要用于．配制巧克力、咖啡、肉类和坚果类等香精。
MOL 文件:108-50-9.mol
方法一:由1，2-二氨基丙烷缩聚后用色层柱使2，6-二甲基吡嗪从2，5-二甲基吡嗪中分离出来。
海关编码:29339990
参考质量标准:FCC，1996 含量 ≥98.0% 熔程 35～40℃ 灼烧残渣(GT-27) ≤0.1% 含水量(同"03512”) ≤0.5% 相对密度(d 50 ) 0.965
Alfa Aesar:2,6-二甲基哌嗪,99% 2,6-Dimethylpyrazine, 99%(108-50-9)
毒性:GRAS(FEMA) LD 50 1080mg/kg(小鼠)。
FEMA:3273
使用限量:FEMA(mg/kg)：软饮料10；冷饮10；糖果10；焙烤食品10；布丁类10；肉、肉沙司、汤10；乳制品10；谷类10。
食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称允许使用该种添加剂的食品中文名称添加剂功能最大允许使用量（g/kg）最大允许残留量（g/kg） 2，6-二甲基吡嗪食品食品用香料用于配制香精的各香料成分不得超过在GB 2760中的最大允许使用量和最大允许残留量
检测方法:GC,NMR
TCI Shanghai:2,6-二甲基吡嗪 2,6-Dimethylpyrazine,>;98.0%(GC)(T)(108-50-9)
Acros Organics:2,6-二甲基吡嗪 2,6-Dimethylpyrazine, balance 2,5-isomer, 96%(108-50-9)