2-Chloropyridine 2-氯吡啶
CAS 109-09-1 MFCD00006228
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} Building Blocks, C5, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Pyridines
产品应用
- 医药、杀菌剂等,有机合成的中间体。
相关文献及参考
- Reaction with the unimetal suberbase complex formed from 2 mol of n-BuLi and I mol of 2-(Dimethylamino)ethanol, B23616, in hexane, gives products resulting from apparent metallation at the 6-position, providing useful access to 6-functionalized 2-chloropyridines: Org. Lett., 2, 803 (2000). See also 2-Methoxypyridine, A13675, for a similar effect.
- Beilstein: 20,V,5,402
安全信息
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
- R50 Very toxic to aquatic organisms 对水生生物极毒
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
GHS Symbol
- H315 Causes skin irritation 会刺激皮肤
- H301+H331
- H310 Fatal in contact with skin 皮肤接触致命
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P301+P310
- P302+P350
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 48 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Liver - fatty liver degeneration REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 195
TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 ppm/4H TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Liver - other changes REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 11,361,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 130 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Liver - fatty liver degeneration REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 11,361,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 110 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic Liver - other changes REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 11,361,1967
TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 1980 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 301,57,1993
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 400 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 301,57,1993
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 5 mg/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 176,185,1987
TYPE OF TEST : Micronucleus test TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 1920 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 301,57,1993
TYPE OF TEST : Sex chromosome loss and nondisjunction TEST SYSTEM : Yeast - Saccharomyces cerevisiae DOSE/DURATION : 4000 ppm REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 163,23,1986
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 1920 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 301,57,1993
其他信息
- 2-氯吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 110015000 2-氯吡啶 2-Chloropyridine 99% 500 ML 973元 2010/06/21 110010025 2-氯吡啶 2-Chloropyridine 99% 2.5 LT 3865元 2010/06/21 110011000 2-氯吡啶 2-Chloropyridine 99% 100 ML 255元
- 用途二:防霉剂如吡硫霉净的中间体。
- 用途三:医药、杀菌剂等,有机合成的中间体。
- Sigma Aldrich:109-09-1(sigmaaldrich)
- Hazard Note:Toxic
- 能随水蒸气挥发。溶解度: 27 g/l 水(20°C) ,>50 g/100ml 乙醇, 溶于醚。
- 类别:有毒物品
- MSDS 信息:2-氯吡啶(109-09-1).msds
- 灭火剂:干粉, 泡沫, 砂土
- 急性毒性:吸入-大鼠 LCL0: 100 PPM/4小时; 口服-小鼠 LD50: 110 毫克/公斤
- 蒸气压:1.7 mm Hg ( 20 °C)
- 上游原料:吡啶 --> 2-氨基吡啶
- 用途一:用于医药、杀虫剂、有机合成
- MOL 文件:109-09-1.mol
- 储运特性:库房通风低温干燥; 与氧化剂, 食品分开储运
- 下游产品:2-吗啉代吡啶-3-醛 --> 2-氯-3-吡啶甲醛 --> 二苯基-2-吡啶膦 --> 2-氯-4-硝基吡啶 N-氧化物 --> 4-吡啶-2-异恶唑-5-胺 --> 2-氯-6-三氟甲基烟酸 --> 氯吡脲 --> 5-氨基甲基-2-氯吡啶 --> N-(4-硝基吡啶-2-基)乙酰胺 --> 2-氨基-4-硝基吡啶 --> 2-乙酰氨基-4-硝基吡啶-N-氧化物 --> 2-氯吡啶-N-氧化物 --> 2-氨基-4-硝基吡啶-N-氧化物 --> 2-氯-4-氨基吡啶盐酸盐 --> 吡丙醚 --> 2-氯-4-硝基吡啶 --> 2-氯-3-(2-硝基苯甲酰氨基)吡啶 --> 双(1-羟基-1H-吡啶-2-硫代硫酸-O,S)铜
- 可燃性危险特性:可燃; 燃烧产生有毒氧化氮, 氯化物气体
- 检测方法:HPLC,NMR
- 图谱信息:2-氯吡啶(109-09-1)红外图谱(IR1) 2-氯吡啶(109-09-1)核磁图( 13 CNMR) 2-氯吡啶(109-09-1)核磁图( 1 HNMR) 2-氯吡啶(109-09-1)质谱(MS)
- Acros Organics:2-氯吡啶 2-Chloropyridine, 99%(109-09-1)
- 毒性分级:高毒
- Alfa Aesar:2-氯吡啶,99% 2-Chloropyridine, 99%(109-09-1)
- 外观性质:无色液体。
- 海关编码:29333999
- 方法一:用2-氨基吡啶经桑德曼尔反应制得。