Thymidine 胸苷
CAS 50-89-5 MFCD00006537
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Biochemicals and Reagents, Nucleosides, Nucleosides, Nucleotides, Oligonucleotides
- {SNA} Core B
- {SNA} Core Bioreagents,
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Culture, Conditioned Media, Media Supplements and Reagents, Hybridoma Reagents, Miscellaneous Reagents and Supplements, Reagents and Supplements,
- {SNA} Conditioned Media, Media Supplements and Reagents, Hybridoma Reagents,
- {SNA} Core Bioreagen
产品应用
- 主要用于抗艾滋病药物(如齐多呋啶、石达呋啶)的制备
相关文献及参考
- [2]. FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5.FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5.
- [3]. Izeradjene K, et al. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independentdeletion of superantigen-reactive peripheral T cells. Int Immunol. 2001 Jan;13(1):85-93.
- Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15
- Short: III/10a Title: Structure Data of Organic Crystals: C ... C 15 Author: Schudt-Weitz, G.; Strell, I. E
安全信息
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
GHS Symbol


- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312
- P305+P351+P338
- P330 Rinse mouth. 漱口
- P501 Dispose of contents/container to..… 处理内容物/容器.....
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2512 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 207,504,1978
TYPE OF TEST : DNA inhibition ROUTE OF EXPOSURE : Oral TEST SYSTEM : Rodent - mouse DOSE/DURATION : 1 gm/kg REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977
{hazard_c
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Fibroblast DOSE/DURATION : 500 umol/L REFERENCE : CYTOAN Cytologia. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1929- Volume(issue)/page/year: 49,667,1984
TYPE OF TEST : Sperm Morphology ROUTE OF EXPOSURE : Intraperitoneal TEST SYSTEM : Rodent - mouse DOSE/DURATION : 4 gm/kg REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 200,249,1988
TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 200 umol/L REFERENCE : BICMBE Biochimie. (SPPIF, B.P.22, F-41353 Vineuil, France) V.53- 1971- Volume(issue)/page/year: 64,809,1982
TYPE OF TEST : Phage inhibition capacity TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 1 gm/L REFERENCE : ZAPOAK Zeitschrift fuer Allgemeine Mikrobiologie. (Akademi
TYPE OF TEST : DNA inhibition TEST SYSTEM : Human Cells - not otherwise specified DOSE/DURATION : 1 mmol/L REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2872,1975
TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Fibroblast
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE : 400 mg/kg SEX/DURATION : female 11 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 32,32A,1985
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - mouse DOSE : 800 mg/kg SEX/DURATION : female 8 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 32,229,1985
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 20 gm/kg SEX/DURATION : male 5 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 200,249,1988
- H302 Harmful if swallowed 吞食有害
其他信息
- 易溶于水、甲醇、热乙醇、热丙醇、热丙酮、热乙酸乙酯、吡啶、冰醋酸中,少量溶于热的氯仿中。水中溶解度:46 g/L (20°C)。
- 下游产品:齐多夫定 --> 司他夫定
- beta-胸苷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 65011580 胸腺核苷 1g 169.4元 2011/04/16 T0233 胸苷 Thymidine 1G 273元 2011/04/16 T0233 胸苷 Thymidine 25G 2100元
- 外观性质:白色或浅色针状结晶.易溶于水、甲醇、热乙醇、热丙醇、热丙酮、热乙酸乙酯、吡啶、冰醋酸中,少量溶于热的氯仿中。水中溶解度:46 g/L (20°C)。熔点:187-189 °C [a]20/D: 18.5° (c=3, H2O)
- Sigma Aldrich:50-89-5(sigmaaldrich)
- MOL 文件:50-89-5.mol
- 图谱信息:beta-胸苷(50-89-5)核磁图( 13 CNMR) beta-胸苷(50-89-5)质谱(MS) beta-胸苷(50-89-5)Raman光谱 beta-胸苷(50-89-5)核磁图( 1 HNMR) beta-胸苷(50-89-5)红外图谱(IR2) beta-胸苷(50-89-5)红外图谱(IR1)
- 用途一:主要用于抗艾滋病药物(如齐多呋啶、石达呋啶)的制备。
- MSDS 信息:Thymine deoxyriboside(50-89-5).msds
- F:10
- 用途二:用作医药中间体,用于合成抗病毒和抗HIV药
- Alfa Aesar:胸苷,99% Thymidine, 99%(50-89-5)
- Acros Organics:胸苷/胸腺嘧啶核苷 Thymidine, 99+%(50-89-5)
- TCI Shanghai:胸腺嘧啶脱氧核苷 Thymidine,>;98.0%(LC)(T)(50-89-5)
- 比旋光度:18.6 ° (c=3, H2O)
- 用途三:主要用于抗艾滋病药物(如齐多呋啶、石达呋啶)的制备