8-Hydroxyquinoline 8-羟基喹啉
CAS 148-24-3 MFCD00006807
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
一流品牌服务
分类
- {SNA} Alphabetical Index of Analytical
- {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antifungal, Biochemicals and Reagents, Building Blocks, C8 to C10, Chemical Structure Class, Chemical Synthesis, Heterocyclic Building Blocks, Inhibits an Enzyme,
- {SNA} A - K,
产品应用
- Used as a lipophilic monoprotic bidentate chelating agent.
相关文献及参考
- Merck:14,4843 Beilstein:21,91
- Short: II/27B
- Chelating ligand.
- Short: II/3
- Merck:14,4843
安全信息
GHS Symbol
- H301 Toxic if swallowed 吞食有毒
- H302 Harmful if swallowed 吞食有害
- H315 Causes skin irritation 会刺激皮肤
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H318 Causes serious eye damage 严重伤害眼睛
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
- H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
- H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P301+P310
- P301+P312
- P301+P312+P330
- P302+P352
- P304+P312
- P304+P340
- P305+P351+P338
- P305+P351+P338+P337+P313
- P308+P313
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P330 Rinse mouth. 漱口
- P332+P313
- P333+P313
- P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
- P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
- R22 Harmful if swallowed 吞咽有害
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors REFERENCE : BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 11,212,1957
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 33 gm/kg/82W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - ovarian tumors REFERENCE : ARPAAQ Archives of Pathology. (Chicago, IL) V.5(3)-50(3), 1928-50; V.70-99, 1960-75. For publisher information, see APLMAS. Volume(issue)/page/year: 79,245,1965
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 7200 mg/kg/50W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Reproductive - Tumorigenic effects - ovarian tumors REFERENCE : VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 16(8),67,1970
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 29 gm/kg/48W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - testicular tumors REFERENCE :
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 83600 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 1,150,1946
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Roden
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1210 mg/m3/6H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 11,497,1992
TYPE OF TEST : LD20 - Lethal Dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 1205 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 20,413,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 19
TYPE OF TEST : DNA inhibition TEST SYSTEM : Human HeLa cell DOSE/DURATION : 25 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 92,427,1982
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 10 ug/plate REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 7500 ug/L REFERENCE : SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 236,933,1987
TYPE OF TEST : DNA adduct TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 10 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211
TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 2600 ug/L REFERENCE : SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 236,933,1987
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Bacillus subtilis DOSE/DURATION : 10 mmol/L REFERENCE : FAVUAI Fiziologicheski Aktivnye Veshchestva. Physiologically Active Substances. (Izdatel'stvo Naukova Dumka, Kiev, USSR) No.1- 1966- Volume(issue)/page/year: 6,118,19
TYPE OF TEST : Cytogenetic analysis ROUTE OF EXPOSURE :
其他信息
- 用途三:沉淀和分离金属离子的沉淀剂和萃取剂,能与下列金属离子络合:Cu+2、Be+2、Mg+2、Ca+2、Sr+2、Ba+2、Zn+2、Cd+2、Al+3、Ga+3、In+3、Tl+3、Yt+3、La+3、Pb+2、B+3、Sb+3、Cr+3、MoO+22、Mn+2、Fe+3、Co+2、Ni+2、Pd+2、Ce+3.
- 下游产品:5-甲氧基甲基-2,3-吡啶二羧酸 --> 8-羟基喹啉-2-羧酸 --> 注射用核糖核酸 --> 8-羟基喹啉铜 --> 8-羟基喹啉-2-甲腈 --> 喹碘方 --> 8-羟基喹啉二硫代磷酸酯络合物 --> 5,7-二氯-8-羟基喹啉 --> 8-羟基喹啉-5-磺酸 --> 5,7-二碘-8-羟基喹啉 --> 5,7-二溴-8-羟基喹啉 --> 5-氯-8-羟基喹啉
- MSDS 信息:8-Quinolinol(148-24-3).msds
- Alfa Aesar:8-羟基喹啉,ACS 8-Hydroxyquinoline, ACS(148-24-3)
- 用途二:该品是卤化喹啉类抗阿米巴药物的中间体,包括喹碘仿、氯碘喹啉、双碘喹啉等。这类药物通过抑制肠内共生菌而发挥抗阿米巴作用,对阿米巴痢疾有效,对肠道外阿米巴原虫无影响。近年来国外报道本类药物能引起亚急性脊髓视神经病,故该药在日本和美国已禁用,双碘喹啉引起此病比氯碘喹啉较少见。8-羟基喹啉也是染料、农药的中间体。其硫酸盐和铜盐是优良的防
- MOL 文件:148-24-3.mol
- Acros Organics:8-羟基喹啉 8-Hydroxyquinoline, for analysis ACS(148-24-3)
- 8-羟基喹啉价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30104082 8-羟基喹啉;8-氢氧化喹啉;8-羟基氮(杂)萘;邻羟基氮(杂)萘 25g 64元 2011/08/23 30104014 8-羟基喹啉;8-氢氧化喹啉;8-羟基氮(杂)萘;邻羟基氮(杂)萘 25g 14元 2011/08/23 30104017 8-羟基喹啉;8-氢氧化喹啉;8-羟基氮(杂)萘;邻羟基氮(杂)萘 250g 120元
- 方法一:由邻氨基苯酚经环合反应制得。将甘油加入耐酸反应锅内,在搅拌下缓缓加入浓硫酸,同时将
- 8-Hydroxyquinoline is a monoprotic bidentate chelating agent The reaction of 8-hydroxyquinoline with aluminium(III) results in Alq3, a common component of organic light-emitting diodes (OLED's). Variations in the substituents on the quinoline rings affect its luminescent properties. 8-Hydroxyquinoline is employed in precipitating and separating metals, the preparation of fungicides, and as a dye
- 用途二:该品是卤化喹啉类抗阿米巴药物的中间体,包括喹碘仿、氯碘喹啉、双碘喹啉等。这类药物通过抑制肠内共生菌而发挥抗阿米巴作用,对阿米巴痢疾有效,对肠道外阿米巴原虫无影响。近年来国外报道本类药物能引起亚急性脊髓视神经病,故该药在日本和美国已禁用,双碘喹啉引起此病比氯碘喹啉较少见。8-羟基喹啉也是染料、农药的
- Sigma Aldrich:148-24-3(sigmaaldrich)
- 用途一:用作医药中间体,是合成克泻痢宁、氯碘喹啉、扑喘息敏的原料,也是染料、农药中间体
- {C
- Hazard Note:Harmful/Irritant
- 图谱信息:8-羟基喹啉(148-24-3)Raman光谱 8-羟基喹啉(148-24-3)核磁图( 1 HNMR) 8-羟基喹啉(148-24-3)质谱(MS) 8-羟基喹啉(148-24-3)核磁图( 13
- 海关编码:29334