4-Nitrobenzoic acid 对硝基苯甲酸
CAS 62-23-7 MFCD00007352
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Building Blocks, C7, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Organic Building Blocks
- {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; carboxylic acid; 1fragment
产品应用
- 检验生物碱,标定标准碱溶液。
相关文献及参考
- Short: II/27B
- Selective reduction of the carboxyl group to the alcohol can be achieved in 94% yield using Benzyltriethylammonium borohydride, B24952, in combination with TMS chloride. Esters are unaffected under these conditions: Synth. Commun., 20, 907 (1990). See also, J. Chem. Soc., Chem. Commun., 903 (1989).
- Short: II/27C
- Beilstein:9,389
安全信息
GHS Symbol
- S39 Wear eye/face protection 戴眼睛/面孔保护装置;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P332+P313
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P301+P312+P330
- P302+P350
- P337+P313
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P308+P313
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
- P305+P351+P338+P337+P313
- P308+P311
- P284 Wear respiratory protection.? 佩戴呼吸保护装置。
- P405 Store locked up. 上锁保管。
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- H318 Causes serious eye damage 严重伤害眼睛
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 45063 mg/kg/2Y-C TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-442,1994
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 880 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - aggression REFERENCE : CRSBAW Comptes Rendus des Seances de la Societe
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1960 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold REFERENCE : CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 160,1097,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1210 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold REFERENCE : CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 160,1097,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1470 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - aggression REFERENCE : CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(
TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 1 gm/L REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,269,1987
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 875 mg/L REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,269,1987
TYPE OF TEST : DNA repair TEST SYSTEM : Bacteria - Bacillus subtilis DOSE/DURATION : 50 ug/disc REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,11,1986
TYPE OF TEST : Body fluid assay TEST SYSTEM : Rodent - rat Bacteria - Salmonella typhimurium DOSE/DURATION : 400 mg/kg/4D REFERENCE : PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 72,4607,1975
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 1 mg/plate REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher informatio
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 100 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 137,71,1984
其他信息
- 用途四:该品是医药、染料、兽药、感光材料等有机合成的中间体。用于生产盐酸普鲁卡因、普鲁卡因胺盐酸盐,对氨甲基苯甲酸、叶酸、苯佐卡因、退嗽、头孢菌素V、对氨基苯甲酰谷氨酸、贝尼尔,以及生产活性艳红M-8B、活性红紫X-2R以及滤光剂、彩色胶片成色剂、金属表面除锈剂、防晒剂等。
- 用途五:检验生物碱,标定标准碱溶液。
- 方法一:由对硝基甲苯氧化而得,氧化剂可采用重铬酸钠、空气、锰矿粉、硝酸
- TCI Shanghai:4-硝基苯甲酸 4-Nitrobenzoic Acid,>;99.0%(GC)(T)(62-23-7)
- 用途三:用作化学试剂
- 对硝基苯甲酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30132326 4-硝基苯甲酸;对硝基苯甲酸 100g 35元 2011/04/16 N0156 4-硝基苯甲酸 4-Nitrobenzoic Acid 25G 117元 2011/04/16 N0156 4-硝基苯甲酸 4-Nitrobenzoic Acid 500G 393元
- 下游产品:对氨基苯甲酸 --> 6-羟甲基喹啉 --> 4-硝基苯甲酰氯 --> 4-氨基苯甲脒二盐酸盐 --> 4-氨基苯甲酸甲酯 --> 4,4’-二脒基重氮氨基苯二乙尿酸 --> 鲨肝醇 --> 對胺苯甲醯胺苯 --> 对氨基苯甲酰胺 --> 奥布卡因盐酸盐 --> 对硝基苯甲腈 --> N-(4-氨基苯甲酰)-L-谷氨酸 --> 丁胺卡因 --> 对氨基苯甲酸异丙酯 --> 盐酸普鲁卡因 --> 3,4-二氨基苯甲酸 --> 4-氨基邻苯二甲酸 --> 对硝基苯甲酸乙酯 --> 奴夫卡因 --> 对硝基苯甲酸甲酯
- 防护措施:有毒。对皮肤有刺激性。其钠盐的小鼠LD10mg/kg。生产设备要密闭,防止泄漏。操作人员应穿戴防护用具。
- Sigma Aldrich:62-23-7(sigmaaldrich)
- 用途二:用于制麻醉剂盐酸普鲁卡因和染料中间体,也可制取滤光剂
- MOL 文件:62-23-7.mol
- 上游原料:重铬酸钠 --> 4-硝基甲苯 --> 氯霉素 --> 锰矿粉 --> 1-对硝基苯基-2-氨基-1,3-丙二醇
- Acros Organics:4-硝基苯甲酸 4-Nitrobenzoic acid, 99+%(62-23-7)
- 海关编码:29163900
- 能升华。溶于醇、醚和二甲替甲酰胺,1g溶于2380ml水、110ml乙醇、12ml甲醇、150ml氯仿、45ml乙醚、20ml丙酮。微溶于水、苯和二硫化碳,不溶于石油醚。低毒,半数致死量(大鼠,经口)1960mg/kg。有刺激性。
- MSDS 信息:对硝基苯甲酸(62-23-7).msds
- 用途一:用作医药中间体,也是生产染料的原料
- 常规方法:采用铁桶、纤维板桶或麻袋内衬塑料袋包装。每桶(袋)净重20kg或40kg。贮存在阴凉、通风、干燥处,防热、防晒。按有毒化学品规定贮运。
- Alfa Aesar:对硝基苯甲酸,99% 4-Nitrobenzoic acid, 99%(62-23-7)
- 外观性质:黄色结晶粉末, 无臭, 能升华。
- 方法一:由对硝基甲苯氧化而得,氧化剂可采用重铬酸钠、空气、锰矿粉、硝酸等等。以对硝基甲苯为原料,在硫酸存在下,于55℃以重铬酸钠进行氧化反应,生成对硝基苯甲酸。反应液经过滤、离心脱水、水洗干燥,即得成品。另外,利用氯霉素生产中的右旋物1-对硝基苯基-2-氨基-1,3-丙二醇,很容易用硝酸氧化得到对硝基苯甲酸。
- 标准值 不确定度 单位