3-Aminophenol 3-氨基苯酚
CAS 591-27-5 MFCD00007786
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Building Blocks, C6 to C8,
- {SNA} A, A-B, AM to AQ, All alphabetically sorted, Alphabetical Index of Analytical Standards, Amines, Analytical Standards,
- A, A-B, AM to AQ, Alpha sort, Alphabetic, Amines, Analytical Standards, Analytical/Chromatography, Aromatics, Chemical Class, Chromatography, Environmental Standards, Pesticides & Metabolites
- {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, Pharmaceutical Secondary Standards, Pharmaceutical Standards
- {SNA} A-B,
- {SNA} Additional Standards,
- {SNA} Building Blocks,
产品应用
- 有机合成。染料和对氨基水杨酸的中间体。
相关文献及参考
- Short: II/27B
- Merck:14,460
- Merck:14,460 Beilstein:13(3)931
- Short: II/3
安全信息
GHS Symbol
- H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
- H302+H332
- H332 Harmful if inhaled 吸入有害
- H302 Harmful if swallowed 吞食有害
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312
- P301+P312+P330
- P302+P350
- P304+
- P304+P340
- P305+P351+P338
- P332+P313
- P337+P313
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
- R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
- R51/53
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 225 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 50(3),4,1985
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 131,151,1961
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1162 mg/m3 TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - excitement Lungs, Thorax, or Respiration - other changes REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(1),49,1988
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 924 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - excitement Lungs, Thorax, or Respiration - other ch
TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 190 umol/L REFERENCE : CRTOEC Chemical Research in Toxicology. (American Chemical Soc., Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC 20037) V.1- 1988- Volume(issue)/page/year: 4,151,1991
TYPE OF TEST : Sex chromosome loss and nondisjunction TEST SYSTEM : Mold - Neurospora crassa DOSE/DURATION : 220 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 167,35,1986
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 3333 ug/plate REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988
TYPE OF TEST : Cytogenetic analysis ROUTE OF EXPOSURE : Inhalation TEST SYSTEM : Rodent - rat DOSE/DURATION : 28300 ug/m3/24H REFERENCE : BZARAZ Biologicheskii Zhurnal Armenii. Biological Journal of Armenia. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.19- 1966- Volume(issue)/page/year: 40,62,1987
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE : 1245 mg/kg SEX/DURATION : female 1-20 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 48(9),19,1983
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE : 1245 mg/kg SEX/DURATION : female 1-20 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 48(9),19,1983
其他信息
- 图谱信息:3-氨基苯酚(591-27-5)核磁图( 13 CNMR) 3-氨基苯酚(591-27-5)核磁图( 1 HNMR) 3-氨基苯
- 灭火剂:二氧化碳、砂土、泡沫、雾状水、干粉
- MOL 文件:591-27-5.mol
- 防护措施:氨基苯酚分子内存在两个有毒基团,所以具有苯胺和苯酚双重毒性。可经皮肤吸收并引起皮炎,能引起高铁血红蛋白症和哮喘。小鼠经口LD50为4.5mg/kg。
- 刺激数据:皮肤-兔子 12.5 毫克/24小时 轻度; 眼睛-兔子 100 毫克/24 小时 中度
- 方法二:以间氨基苯磺酸为原料,经碱熔、酸化而得。将间氨基苯磺酸用水搅拌成浆状,加热至60℃,滴加烧碱溶液,使pH为7-8,过滤得间氨基苯磺酸钠盐溶液。在碱熔锅内投入固碱或液碱,加热熔化或蒸浓,在275℃逐步加入间氨基苯磺酸钠盐溶液。加毕,继续保持275℃反应75min。将物料稀释于亚硫酸钠洗液中,过滤分离亚硫酸钠。分离亚硫酸钠后的间氨基苯酚钠溶液在50℃以下加入31%盐酸至中性。降温到35℃,析出粗间氨基酚,过滤,将滤饼加入蒸馏锅,真空蒸馏,馏出的精制间氨基苯酚经制
- 可燃性危险特性:明火可燃; 受热分解有毒氮氧化物和氯化物气体
- 用途三:用于有机合成
- 下游产品:间苯二酚 --> C545T --> 4-氨基水杨酸 --> 赤藓红B --> 罗丹明 123 --> 7-羟基喹啉 --> 间溴苯酚 --> 香豆素 314T --> 7-氨基-4-甲基香豆素 --> 尼多克罗 --> 间氨基苯乙醚 --> 3-[(甲氧羰基)氨基]苯基-N-(3-甲基苯基)氨基甲酸酯 --> 9-醛基-8-羟基-1,1,7,7-四甲基久洛尼定 --> 罗丹明 --> 灭锈胺 --> 直接黑168 --> 香豆素 151 --> 3-氨基苯异丙醚 --> 荧光增白剂SWN --> 3-羟基-N,N-二甲基苯胺 --> 对氨基水杨酸钠
- 类别:有毒物品
- 海关编码:29222900
- 用途四:间氨基苯酚是杀菌剂灭锈胺、氟酰胺的中间体。
- 方法一:其制备方法是将间氨基苯磺酸用水搅拌成浆状,加热至60℃,滴加烧碱溶液(pH=7~8),过滤得间氨基苯磺酸盐,将该盐溶液慢慢加到浓烧碱水溶液中,于270℃反应至Na 2 SO 3 不再生成为止,加水稀释过滤,分去Na 2 SO 3 残渣,然后过热水稀释碱溶液,稀释温度保持在100~110℃进行热过滤,滤液用30%工业盐酸酸化,温度不高于90℃,酸化终点pH=7~8,酸化后降温至20℃以下,静置,结晶,过滤,再经真空蒸馏即得成品。
- Alfa Aesar:3-氨基苯酚,98+% 3-Aminophenol, 98+%(591-27-5)
- 3-氨基苯酚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80005324 3-氨基酚;间氨基酚;3-羟基苯胺;3-氨基-1-羟基苯 25g 25.7元 2011/04/16 A0383 3-氨基苯酚 3-Aminophenol 25G 187元 2011/04/16 A0383 3-氨基苯酚 3-Aminophenol 500G 862元
- 用途二:用作染料及医药中间体,用于制造偶氮染料
- 职业标准:STEL 1 毫克/立方米
- 色指数:76545
- TCI Shanghai:3-氨基苯酚 3-Aminophenol,>;98.5%(T)(591-27-5)
- 用途六:有机合成。染料和对氨基水杨酸的中间体。
- 用途五:染料中间体,用于制造偶氮染料,也可用于毛皮染料,如毛皮棕EG、毛皮黄EG等。医药中间体,用于生产抗结核药对氨基水杨酸。也用于生产抗氧剂、稳定剂、显影剂和彩色胶片,还用于头发染色等。
- 储运特性:库房通风低温干燥; 与食品原料分开储运
- MSDS 信息:3-氨基苯酚(591-27-5).msds
- {Chemicalbook
- 见光易变色。水中溶解度: 3