2,4-Dichloro-5-sulfamoylbenzoic acid 2,4-二氯-5-磺酰胺基苯甲酸
CAS 2736-23-4 MFCD00007931
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资金保障
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分类
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds
- {SNA} Building Blocks, Chemical Synthesis, Organic Building Blocks, Sulfonamides/Sulfinamides, Sulfur Compounds
产品应用
- 2,4-Dichloro-5-sulfamoylbenzoic Acid is a chlorinated sulfamoylbenzoic acid with diuretic acid.
相关文献及参考
- Shani, J. et al.: Pharmacology, 26, 172 (1983); Lebedev, A.A. et al.: Khim.-Farm. Zhur., 19, 1205 (1985);
安全信息
- S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P264+P265
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P350
- P302+P352
- P302+P352+P332+P313+P362+P364
- P304+P340
- P305+P351+P338
- P305+P351+P338+P310
- P305+P354+P338
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P317
- P319
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P332+P313
- P332+P317
- P337+P313
- P337+P317
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- P362+P364
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H315 Causes skin irritation 会刺激皮肤
- H318 Causes serious eye damage 严重伤害眼睛
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 15 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 19,697,1985
其他信息
- Alfa Aesar:2,4-二氯-5-氨磺酰基苯甲酸,98% 2,4-Dichloro-5-sulfamoylbenzoic acid, 98%(2736-23-4)
- Acros Organics:2,4-二氯-5-磺酰胺基苯甲酸 2,4-Dichloro-5-sulfamoylbenzoic acid, 98%(2736-23-4)
- MSDS 信息:5-(Aminosulfonyl)-2,4-dichlorobenzoic acid(2736-23-4).msds
- MOL 文件:2736-23-4.mol
- TCI Shanghai:2,4-二氯-5-磺酰胺苯甲酸 2,4-Dichloro-5-sulfamoylbenzoic Acid,>;96.0%(T)(2736-23-4)
- 用途一:用于合成呋噻咪、速尿等药物
- 用途二:速尿的中间体。
- 2,4-二氯-5-磺酰胺基苯甲酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D2541 2,4-二氯-5-磺酰胺苯甲酸 2,4-Dichloro-5-sulfamoylbenzoic Acid 25G 331元 2010/05/25 B24589 2,4-二氯-5-氨磺酰基苯甲酸, 98% 2,4-Dichloro-5-sulfamoylbenzoic acid, 98% 50g 351元 2010/05/25 B24589 2,4-二氯-5-氨磺酰基苯甲酸, 98% 2,4-Dichloro-5-sulfamoylbenzoic acid, 98% 250g 1025元
- 下游产品:呋噻米
- 图谱信息:2,4-二氯-5-磺酰胺基苯甲酸(2736-23-4)核磁图( 1 HNMR) 2,4-二氯-5-磺酰胺基苯甲酸(2736-23-4)质谱(MS) 2,4-二氯-5-磺酰胺基苯甲酸(2736-23-4)核磁图( 13 CNMR) 2,4-二氯-5-磺酰胺基苯甲酸(2736-23-4)红外图谱(IR1)
- 上游原料:氯磺酸 --> 苯磺酰氯 --> 2,4-二氯苯甲酸
- 方法一:用2,4-二氯苯甲酸以氯磺酸氯磺化,生成2,4-二氯-5-羧基苯磺酰氯,再以氨水胺化制得该品。