Hexamethylphosphorous Triamide 三(二甲胺基)膦
CAS 1608-26-0 MFCD00008301
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Catalysis and Inorganic Chemistry, Chemical Synthesis, Phosphine Compounds, Phosphine Ligands
- Phosphorylating and Phosphitylating Agents
- {uni_hamburg} no charge; 1fragment
- Miscellaneous Reagents
产品应用
- Reagent combination with CCl4 for the conversion of hydroxyl groups to the corresponding chlorides; hydroxyl group activation; dehydrations.
相关文献及参考
- Has also been used for a variety of other reductions including that of ozonolysis intermediates: Helv. Chim. Acta, 50, 2387 (1967), and of primary alkyl nitro compounds to nitriles: Synthesis, 36 (1979). Bromohydrins can be converted to alkenes, by reductive elimination from their triflate esters: J. Am. Chem. Soc., 102, 1433 (1980):
- Reacts with BrCCl3 to give dichloromethylenephosphorane Cl2C=PPh3, which undergoes Wittig reaction with aldehydes to give 1,1-dichloroalkenes, giving better results than the CCl4/PPh3 combination: Tetrahedron Lett., 1237, 1239 (1977); Synthesis, 554 (1980). Similarly, with Br2CF2, the CF2 group can be transferred to both aldehydes and ketones: J. Fluorine Chem., 1, 123 (1971); Synth. Commun., 3, 197 (1973).
- Reduces aromatic aldehydes to symmetrical epoxides in good yield: J. Am. Chem. Soc., 85, 1884 (1963). Both cis- and trans-isomers are formed. For list of examples, see: Org. Synth. Coll., 5, 358 (1973). Under suitable conditions, reaction of the intermediate with a second aldehyde can lead to mixed deoxybenzoins or diaryl enamines: Synthesis, 225 (1991).
- Ryu, H., et al.: J. Mat. Sci., 41, 8265 (2006),
- Short: II/2
- Short: II/25D
安全信息
GHS Symbol
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- R45 May cause cancer 可能致癌
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R46 May cause inheritable genetic damage 可能引起遗传基因损害
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
- R10 Flammable 易燃
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P233 Keep container tightly closed. ?保持容器密闭。
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P241+P242+P243
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312+P330
- P302+P352+P312+P362+P364
- P303+P361+P353
- P304+P340+P312
- P305+P351+P338
- P305+P351+P338+P337+P313
- P308+P313
- P332+P313
- P337+P313
- P370+P378
- P403+P235
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H226 Flammable liquid and vapour 易燃液体和蒸气
- H340 May cause genetic defects 可能导致遗传性缺陷
- H350 May cause cancer 可能致癌
TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Oral TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 1 mmol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 212,193,1989
TYPE OF TEST : Morphological transformation TEST SYSTEM : Rodent - hamster Kidney DOSE/DURATION : 2500 ug/L REFERENCE : BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 38,418,1978
其他信息
- TCI Shanghai:三(二甲胺基)膦(可能有沉淀物) Tris(dimethylamino)phosphine (may contain precipitate),>;95.0%(GC)(1608-26-0)
- 上游原料:氢氧化钠 --> 盐酸 --> 乙醚 --> 四氢呋喃 --> 正己烷 --> 氢化铝锂 --> 三氯化磷 --> 二甲胺 --> 环己烷 --> N,N-二甲基三甲基硅胺
- 下游产品:N-二甲基-1,1-螺旋茚丹-7,7-二基磷铵 --> N-二甲基-[(S)-1,1'-螺二氢茚-7,7'-二基]亚磷酰胺
- Acros Organics:六甲基磷酰三胺 Hexamethylphosphorous triamide, 97%(1608-26-0)
- Hazard Note:Irritant
- 用途一:有机合成中间体。
- 检测方法:PNMR,NMR
- Alfa Aesar:己甲基亚磷三酰胺,97% Hexamethylphosphorous triamide, 97%(1608-26-0)
- MOL 文件:1608-26-0.mol
- 海关编码:29299000
- 方法一:将137.3g(1.0mol)三氯化磷溶于1.5L无水乙醚,搅拌,冷至1-5℃,通入过量的无水二甲胺气体,控制通气速度,使反应温度不超过15℃,通气毕,在氮氛中于室温放置过夜,滤除二甲胺盐酸盐,滤液减压蒸发回收乙醚,得152-154g,油状的六甲基亚磷酰三胺,收率94-95%。
- Sigma Aldrich:1608-26-0(sigmaaldrich)
- F:10
- MSDS 信息:Tris(dimethylamino)phosphine(1608-26-0).msds
- 存储注意事项:氮气保护
- 图谱信息:三(二甲胺基)膦(1608-26-0)核磁图( 13 CNMR) 三(二甲胺基)膦(1608-26-0)核磁图( 1 HNMR) 三(二甲胺基)膦(1608-26-0)红外图谱(IR1) 三(二甲胺基)膦(1608-26-0)质谱(MS)
- 敏感性:Moisture Sensitive
- 三(二甲胺基)膦价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 T1317 三(二甲氨基)膦(可能有沉淀物) Tris(dimethylamino)phosphine (may contain precipitate) 250ML 6150元 2014/06/02 T1317 三(二甲氨基)膦(可能有沉淀物) Tris(dimethylamino)phosphine (may contain precipitate) 25ML 1060元 2010/06/21 162480500 三(二甲胺基)膦 Hexamethylphosphorous triamide 97% 50 ML 3257元