N-Methylacetamide N-甲基乙酰胺
CAS 79-16-3 MFCD00008683
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {uni_hamburg} no charge; amide; 1fragment
- {SNA} Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Protected Amines
产品应用
- 因它具有溶解其它有机物的优良机物性能的优良性能,所以在有机合成上常用作溶剂。N-甲基乙酰胺对于某些化学反应有催化作用,在非极性溶剂中又是一个脱酸剂。
相关文献及参考
- Beilstein:4,58
- Short: II/25C
- Short: II/27B
安全信息
GHS Symbol
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P350
- P305+P351+P338
- P308+P313
- P332+P313
- P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H303 May be harmfully swallowed 吞食可能有害
- H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4380 mg/kg TOXIC EFFECTS : Nutritional and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - body temperature decrease REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16,472,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 4,219,1962
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Bird - chicken DOSE/DURATION : 14 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1242,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 18,645,1968
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TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 10 gm/L REFERENCE : APHGAO Acta Pharmaceutica Hungarica. (Kultura, POB 149, H-1389 Budapest, Hungary) 1953- Adopts V.24 in 1955. Volume(issue)/page/year: 56,97,1986
TYPE OF TEST : DNA inhibition ROUTE OF EXPOSURE : Unreported TEST SYSTEM : Rodent - mouse DOSE/DURATION : 3330 mg/kg REFERENCE : APHGAO Acta Pharmaceutica Hungarica. (Kultura, POB 149, H-1389 Budapest, Hungary) 1953- Adopts V.24 in 1955. Volume(issue)/page/year: 56,97,1986
TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - mouse Cells - not otherwise specified DOSE/DURATION : 66 gm/L REFERENCE : APHGAO Acta Pharmaceutica Hungarica. (Kultura, POB 149, H-1389 Budapest, Hungary) 1953- Adopts V.24 in 1955. Volume(issue)/page/year: 56,97,1986
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 10 gm/L REFERENCE : CRSUBM Cancer Research Supplement. (Baltimore, MD) No.1-4, 1953-56. Volume(issue)/page/year: 3,69,1955
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE : 3250 mg/kg SEX/DURATION : female 6-18 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - body wall Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,1557,1980
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE : 3250 mg/kg SEX/DURATION : female 6-18 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSUR
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE : 2 gm/kg SEX/DURATION : female 15-16 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : 85DJA5 "Malformations Congenitales des Mammiferes," Tuchmann-Duplessis, H., Paris, Masson et Cie, 1971 Volume(issue)/page/year: -,95,1971
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其他信息
- Sigma Aldrich:79-16-3(sigmaaldrich)
- TCI Shanghai:N-甲基乙酰胺 N-Methylacetamide,>;99.0%(GC)(79-16-3)
- Alfa Aesar:N-甲基乙酰胺,99% N-Methylacetamide, 99%(79-16-3)
- 储运特性:库房通风低温干燥
- 方法一:由乙酸乙酯与甲胺反应而得。将乙酸乙酯和65%的甲胺混合,加热至60℃左右,反应4昼夜,至不再有分层现象,即反应完毕。减压蒸馏回收乙醇,收集95-110℃(4.0kPa)馏分而得N-甲基乙酰胺。
- 溶于水、乙醇、苯、醚、氯仿,不溶于石油醚。
- 海关编码:29241900
- 毒性分级:中毒
- MSDS 信息:N-Methylacetamide(79-16-3).msds
- N-甲基乙酰胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M0133 N-甲基乙酰胺 N-Methylacetamide 25G 129元 2014/06/02 M0133 N-甲基乙酰胺 N-Methylacetamide 500G 489元 2010/06/21 126141000 N-甲基乙酰胺 N-Methylacetamide 99+% 100 GR 224元
- 类别:易燃液体
- MOL 文件:79-16-3.mol
- 用途一:用作溶剂,也用于制药
- 下游产品:替罗非班
- 用途二:该品为农药、医药等有机合成的中间体。
- 用途三:因它具有溶解其它有机物的优良机物性能的优良性能,所以在有机合成上常用作溶剂使用在制药工业,使用广泛,如合成孢菌素,就使用它和为溶剂。N-甲基乙酰胺对于某些化学反应有催化作用,在非极性溶剂中又是一个脱酸剂。所以目前使用广泛。
- 图谱信息:N-甲基乙酰胺(79-16-3)质谱(MS) N-甲基乙酰胺(79-16-3)核磁图( 13 CNMR) N-甲基乙酰胺(79-16-3)核磁图( 1 HNMR) N-甲基乙酰胺(79-16-3)Raman光谱 N-甲基乙酰胺(79-16-3)红外图谱(IR1)
- 灭火剂:干粉、泡沫、砂土、水
- Acros Organics:N-甲基乙酰胺 N-Methylacetamide, 99+%(79-16-3)
- 急性毒性:口服- 大鼠 LD50: 5000 毫克/ 公斤
- 可燃性危险特性:易燃; 燃烧产生有毒氮氧化物气体