CAS 108-10-1 MFCD00008938-4-Methyl-2-pentanone 甲基异丁基甲酮 TAO{mole}

4-Methyl-2-pentanone 甲基异丁基甲酮

CAS 108-10-1 MFCD00008938

化学结构图

SMILES: CC(=O)CC(C)C

化学属性

Mol. Formula	C6H12O
Mol. Weight	100.16
Refractive index	1.3940 to 1.3970
Boiling Point	117-118
Density	0.8
Melting Point	-84
Flash Point	17°C(lit.)
TSCA	Yes
Autoignition Point	840 °F
Vapor Density	3.5 (vs air)
Vapor Pressure	15 mmHg ( 20 °C)
Solubility	微溶于水，易溶于多数有机溶剂。
Stability	对湿度敏感

别名和识别编码

Chemical Name	4-Methyl-2-pentanone
Synonym	4-Methylpentan-2-one {LY} 4-Methylpentan-2-one Isobutylmethylketon Ketone, isobutyl methyl MIBK Methyl 2-methylpropyl ketone Methyl isobutyl ketone {} {LY} 4-Methylpentan-2-one {} {} {LY} 4-Methylpentan-2-one {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpen
CAS Number	108-10-1
PubChem Substance ID	7909
EC Number	203-550-1
Beilstein Registry Number	605399
MDL Number	MFCD00008938
Reaxys-RN	605399
Merck Number	5207
Chemical Name Translation	甲基异丁基甲酮
Wiswesser Line Notation	1Y1&1V1
LabNetwork Molecule ID	LN00001729
InChI	InChI=1S/C6H12O/c1-5(2)4-6(3)7/h5H,4H2,1-3H3
Canonical SMILES	CC(CC(C)C)=O

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品牌质保精细包装现货库存一流品牌服务

产品应用

是优良的中沸点溶剂。用作选矿剂；油品脱蜡用溶剂；彩色影片的成色剂，也用作四环素和除虫菊酯类和DDT的溶剂；粘合剂；橡胶胶水；飞机和模型的蒙布漆。对一些无机盐也是有效的分离剂，可从铀中分出钚，从钽分出铌，从铪分出锆。它的过氧化物是聚酯类树脂聚合反应中非常重要的引发剂。也用于有机合成工业。还可用作乙烯型树脂的抗凝剂和稀释剂。

安全信息

GHS Symbol

WGK Germany1

Hazard Codes 3 F,Xn,T

Hazard statements

H332 Harmful if inhaled 吸入有害
H335 May cause respiratory irritation 可能导致呼吸道刺激
H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
H319 Causes serious eye irritation 严重刺激眼睛

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSSA9275000

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P303+P361+P353
P304+P340
P305+P351+P338
P308+P313
P337+P313
P370+P378
P403+P233
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

UN Number 1245 UN1245

Risk Statements

R11 Highly flammable 非常易燃
R20 Harmful by inhalation 吸入有害
R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
R36/37 Irritating to eyes and respiratory system 对眼睛和呼吸系统有刺激性
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性：吸入，皮肤接触和吞食都会产生十分严重的不可逆危险
R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂

Safety Statements

S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
S29 Do not empty into drains 不要排入下水道；
S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；

Packing GroupII

Storage condition 2-8°C {LY} 2-8°C 4°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C

Hazard Class3

Warnings 危化品目录(2015)

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1396 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 51(5),61,1986

TYPE OF TEST            : LC50 - Lethal conc

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton,
   G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82.
   Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
   Volume(issue)/page/year: 2C,4748,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >20 mL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 4/25/1958

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3000 ppm/6H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   8,310,1987

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 300 ppm/6H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   8,310,1987

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3000 ppm/6H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   8,310,1987

Restrict 危险品

其他信息

Acros Organic
所属类别一:食品添加剂: 食用香料（增香剂）: 天然等同香料和人造香
毒性分级:中毒
储运特性:库房通风低温干燥; 轻装轻卸、与氧化剂和酸类
使用限量:FEMA(mg/kg)：软饮料6.3；冷饮6.3；糖果6.3；焙烤食品6.3。适度为限(FDA§172．51
方法三:由异丙叉丙酮经催化选择
4-甲基-2-戊酮价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 80085180 4-甲基-2-戊酮;甲基异丁基酮; 异丁基甲基酮; 异丙基丙酮; 2-异己酮; 2-甲基-4-戊酮 50ml 62元 2011/08/23 80085118 4-甲基-2-戊酮;甲基异丁基酮; 异丁基甲基酮; 异丙基丙酮; 2-异己酮; 2-甲基-4-戊酮 500ml 27元 2011/08/23 80085128 4-甲基-2-戊酮;甲基异丁基酮; 异丁基甲基酮; 异
上游原料:丙酮 --> 氢 --> 磷酸催化剂 --> 石化 --> 4-甲基-2-戊醇 --> 肥料 --> 磷酸氢锆(Ⅳ)(2:1)
所属类别二:农药中间体: 杀鼠剂中间体
爆炸物危险特性:与空气混合可爆
参考质量标准:FCC，1997；FAO/WHO，1998 含量 ≥99.0% 馏程 114～117℃ 相对密度(d 25 25 ) 0.796～0.799 酸值(OT-4) ≤2.0 水分 ≤0.1% 折射率(d 25 25 ) 1.391～1.396
类别:易燃液体
含量分析:按“乙醛(03401)”中含量分析法测定。所取试样量为1.2 g。反应时间改为60 min。每Ml 0.5 mol／L硫酸液相当于4-甲基-2-戊酮(C6H12O)50.08 mg。
用途五:该品是优良的中沸点溶剂。用作选矿剂、油品脱蜡用溶剂、彩色影片的成色剂，也用作四环素和除虫菊酯类和DDT的溶剂、粘合剂、橡胶胶水、飞机和模型的蒙布漆。对一些无机盐也是有效的分离剂，可从铀中分出钚，从钽分出铌，从铪分出锆。它的过氧化物是聚酯类树脂聚合反应中非常重要的引发剂。也用于有机合成工业。还可用作乙烯型树脂的抗凝剂和稀释剂。
Alfa Aesar:4-甲基-2-戊酮,HPLCGrade,99+% 4-Methyl-2-
职业标准:TLV-TWA 50 PPM (205 毫克/ 立方米); STEL 75 PPM (300 毫克/ 立方米)
TCI Shanghai:4-甲基-2-戊酮 4-Methyl-2-pentanone,>;99.5%(GC)(108-10-1)
有芳香酮愉快气味。自然点460℃。能与醇；苯；乙醚及多数有机溶剂混溶，微溶于水。蒸气与空气形成爆炸性混合物，爆炸极限1.4%-7.5%(体积)。
外观性质:水样透明液体, 有令人愉快的酮样香味。
下游产品:邻苯二酚 --> 米力农 --> 多潘立酮 --> 偶氮二异庚腈 --> 洛哌丁胺 --> 孕二烯酮 --> 1-(3,4-二氯苯基)哌嗪 --> 丙环唑 --> 奥沙米特 --> N-(1,3-二甲基丁基)-N'-苯基对苯二胺 --> 福辛普利 --> 盐酸雷尼替丁 --> 氟钽酸钾 --> 五氧化二铌
方法二:由异丙叉丙酮在160～190℃下通过镍催化剂进行轻度氢化而成。由甲基异丁基甲醇氧化而得。
图谱信息:4-
使用限量:FEMA(mg/kg)：软饮料6.3；冷饮6.3；糖果6.3；焙烤食品6.3。适度为限(FDA§172．515，2000)。
急性毒性:口服- 大鼠 LD50: 2080 毫克/ 公斤; 口服- 小鼠 LD50: 2671 毫克/ 公斤
Sigma Aldrich:108-10-1(sigma
MOL 文件:108-10-1.mol