9-(diethylamino)benzo[a]phenoxazin-5-one 9-(二乙胺基)-5H-苯并[a]吩恶嗪-5-酮
CAS 7385-67-3 MFCD00011639
化学结构图
SMILES: CCN(CC)c1ccc2nc3c4ccccc4c(=O)cc-3oc2c1
化学属性
| Mol. Formula | C20H18N2O2 |
|---|---|
| Mol. Weight | 318.37 |
| Density | 1.422 |
| Melting Point | 203-205 |
| Solubility | Soluble in water (Partly miscible), and methanol (1 mg/ml). |
| Stability | 对光线敏感 |
别名和识别编码
| Chemical Name | 9-(diethylamino)benzo[a]phenoxazin-5-one |
|---|---|
| MDL Number | MFCD00011639 |
| CAS Number | 7385-67-3 |
| EC Number | 230-966-0 |
| Beilstein Registry Number | 279110 |
| Synonym | 9-(二乙胺基)-5H-苯并[a]吩恶嗪-5-酮 9-Diethylamino-benzo[a]phenoxazin-5-one 9-diethylamino-5H-benzo(a)phenoxazine-5-one ChemDose™，N,N′-二环己基碳二亚胺浸渍片剂 DCC 浸渍片剂 Nile Blue A Oxazone Nile Red nile red {} {} {} {} {PubChem} nile red {} {} {} {} {} {} {PubChem} nile red |
| PubChem Substance ID | 65182 |
| Reaxys-RN | 279110 |
| Chemical Name Translation | 9-(二乙胺基)-5H-苯并[a]吩恶嗪-5-酮 |
| LabNetwork Molecule ID | LN00196380 |
| InChI | InChI=1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3 |
| Canonical SMILES | O=C1C2=CC=CC=C2C3=NC4=CC=C(N(CC)CC)C=C4OC3=C1 |
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分类
- {SNA} Alphabetical, Core Bioreagents, Fluorescent Indicators and Probes, Fluorescent Labels, Lipophilic and Membrane Probes, N,
- {SNA} Biochemicals and Reagents, Fluorescent Labels, Fluorescent Probes, Labels, Particles and Stains, Luminescent Compounds/Detection, Other Fluorescent Labels, Wavelength Index
- {SNA} Alphabetica
产品应用
- A photostable, lipophilic stain with bright red fluorescence
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R24 Toxic in contact with skin 与皮肤接触有毒
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
- R22 Harmful if swallowed 吞咽有害
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H351 Suspected of causing cancer 怀疑致癌
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H318 Causes serious eye damage 严重伤害眼睛
- H312 Harmful in contact with skin 皮肤接触有害
其他信息
- Sigma Aldrich:7385-67-3(sigmaaldrich)
- Acros Organics:尼罗红 Nile Red, pure, 99%(7385-67-3)
- MOL 文件:7385-67-3.mol
- 尼罗红价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 N0659 尼罗红 Nile Red 500MG 1580元 2011/04/16 N0659 尼罗红 Nile Red 1G 2580元 2010/06/21 415710010 尼罗红 Nile Red 99%, pure 1 GR 4319元
- F:8-10
- 上游原料:乙醇 --> 氢氧化钠 --> 盐酸 --> 乙醚 --> 乙酸 --> 亚硝酸钠 --> 异丙醇 --> 镍 --> 3-羟基-N,N-二乙基苯胺 --> 1,4-萘醌 --> 2-羟基-1,4-萘醌
- TCI Shanghai:尼罗红 Nile Red(7385-67-3)
- Nile Red is an uncharged, hydrophobic, photostable molecule that strongly fluoresces bright red in hydrophobic environments. This lipophilic stain is commonly used for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytofluorometry. Nile Red has been shown to detect the exposure or formation of new hydrophobic surfaces induced by ligand binding to calmodulin, oligomerization of melittin, or unfolding of ovalbumin during early thermal denaturation. This product has been employed to stain cell structures, as well as to visualize and localize colloidal drug carriers. Nile Red's fluorescence is unaffected between pH 4.5 and 8.5 and may be used in dilute concentrations to investigate hydrophobic protein sites.
- 尼罗红价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 N0659 尼罗红 Nile Red 500MG 1580元 2014/06/02 N0659 尼罗红 Nile Red 1G 2790元 2010/06/21 415710010 尼罗红 Nile Red 99%, pure 1 GR 4319元
